Browsing Waterloo Research by Title
Now showing items 629-648 of 2454
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DNA duplex stabilization in crowded polyanion solutions
(Royal Society of Chemistry, 2013-02-14)The melting temperature of duplex DNA is much higher in polyanions than in non-ionic polymers with similar ionic strength, suggesting an additional electrostatic contribution on top of the excluded volume effect. -
DNA stabilized fluorescent metal nanoclusters for biosensor development
(Elsevier, 2014-03-22)Fluorescent silver, gold and copper nanoclusters (NCs) have emerged for biosensor development. Compared to semiconductor quantum dots, there is less concern about the toxicity of metal NCs, which can be more easily conjugated ... -
DNA stabilized silver nanoclusters for ratiometric and visual detection of Hg2+ and its immobilization in hydrogels
(Elsevier, 2013-04-11)DNA oligomers are particularly interesting templates for making silver nanoclusters (AgNCs) as different emission colors can be obtained by varying the DNA sequence. Many AgNCs have been used as Hg2+ sensors since Hg2+ ... -
DNA templated fluorescent gold nanoclusters reduced by Good’s buffer: from blue emitting seeds to red and near infrared emitters
(NRC Research Press, 2015-01-22)DNA-templated fluorescent gold nanoclusters (AuNCs) have been recently prepared showing higher photostability than the silver counterpart. In this work, we examined the effect of pH, DNA length, DNA sequence, and reducing ... -
DNA-Functionalized Gold Nanoparticles in Macromolecularly Crowded Polymer Solutions
(American Chemical Society, 2012-11-15)DNA-functionalized gold nanoparticles (AuNPs) are one of the most commonly used reagents in nanobiotechnology. They are important not only for practical applications in analytical chemistry and drug delivery, but also for ... -
DNA-Functionalized Monolithic Hydrogels and Gold Nanoparticles for Colorimetric DNA Detection
(American Chemical Society, 2010-12-22)Highly sensitive and selective DNA detection plays a central role in many fields of research, and various assay platforms have been developed. Compared to homogeneous DNA detection, surface-immobilized probes allow washing ... -
DNA-Length-Dependent Fluorescence Signaling on Graphene Oxide Surface
(Wiley, 2012-02-10)Fluorescence energy transfer to graphene oxide is studied using covalently linked DNA probes ranging from 4 to 70 base pairs. The characteristic distance and mechanism of energy transfer are reported. -
DNAzyme Hybridization, Cleavage, Degradation and Sensing in Undiluted Human Blood Serum
(American Chemical Society, 2015-04-07)RNA-cleaving DNAzymes provide a unique platform for developing biosensors. However, a majority of the work has been performed in clean buffer solutions, while the activity of some important DNAzymes in biological sample ... -
A DNAzyme requiring two different metal ions at two distinct sites
(Oxford University Press, 2015-12-10)Most previously reported RNA-cleaving DNAzymes require only a single divalent metal ion for catalysis. We recently reported a general trivalent lanthanide-dependent DNAzyme named Ce13d. This work shows that Ce13d requires ... -
Do school physical activity policies and programs have a role in decreasing multiple screen time behaviours among youth?
(Elsevier, 2017-11-29)Screen time in youth has been associated with a wide range of poor health outcomes. Evidence indicates the need to develop physical activity (PA) school policies and programs that are aimed at decreasing youth screen time ... -
Dodging Monsters and Dancing with Dreams: Success and Failure at Different Levels of Approach and Avoidance
(SAGE Publications, 2013-07-01)Many models of motivation suggest that goals can be arranged in a hierarchy, ranging from higher-level goals that represent desired end-states to lower-level means that operate in the service of those goals. We present a ... -
Does AI Remember? Neural Networks and the Right to be Forgotten
(2020-04-14)The Right to be Forgotten is part of the recently enacted General Data Protection Regulation law that affects any data holder that has data on European Union residents. It gives EU residents the ability to request deletion ... -
Does Cox analysis of a randomized survival study yield a causal treatment effect?
(Springer US, 2015-10)Statistical methods for survival analysis play a central role in the assessment of treatment effects in randomized clinical trials in cardiovascular disease, cancer, and many other fields. The most common approach to ... -
Does History Matter? Pioneering Research on Canada's Attitudes Toward Bygone Days
(The LIterary Review of Canada, 2014-05)A book review of 'Canadians and their past' by Margaret Conrad, Kadriye Ercikan, Gerald Friesen, Jocelyn Létourneau, Delphin Muise, David Northrup and Peter Seixas. -
Does Stress-Related Poor Diet Quality Explain Socioeconomic Inequities in Health? A Structural Equation Mediation Analysis in Women and Men
(Oxford University Press, 2021-06)Objectives Individuals with a lower socioeconomic position (SEP) have poorer health than their more advantaged counterparts. Psychosocial stress and diet quality have been shown to individually mediate associations between ... -
Doing the work: Editing Wikipedia as an act of reconciliation
(On Archivy, 2018-08-28)The Truth and Reconciliation Commission of Canada Calls to Action outline the responsibilities of cultural heritage workers to educate both themselves and the general public about the Canadian Indian Residential School ... -
Dose-dependent dissociation of pro-cognitive effects of donepezil on attention and cognitive flexibility in rhesus monkeys
(Elsevier, 2021-11)BACKGROUND Donepezil exerts pro-cognitive effects by non-selectively enhancing acetylcholine (ACh) across multiple brain systems. Two brain systems that mediate pro-cognitive effects of attentional control and cognitive ... -
Double Bubbles Sans Toil and Trouble: Discrete Circulation-Preserving Vortex Sheets for Soap Films and Foams
(Association for Computing Machinery, 2015-08-01)Simulating the delightful dynamics of soap films, bubbles, and foams has traditionally required the use of a fully three-dimensional many-phase Navier-Stokes solver, even though their visual appearance is completely dominated ... -
Driving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfaces
(American Chemical Society, 2015-11-23)Surface forces between inorganic nanoparticles and lipid bilayer is of great relevance to biophysics, medicine, and nanobiotechnology. Adsorbed nanoparticles may influence the fluidity of the underlying lipids, which may ... -
Driving under the influence behaviours among high school students who mix alcohol with energy drinks
(Elsevier, 2018-06-01)Alcohol and energy drinks are commonly used substances by youth in Canada, and are often mixed (AmED). While several studies have shown that AmED can have dangerous effects, less well understood is how AmED is associated ...