Some users are experiencing upload errors at the moment. If you receive a "UWSpace is down for maintenance" error, please email jordan.hale@uwaterloo.ca as soon as possible. We are very sorry for the inconvenience.

Now showing items 1-3 of 3

    • Calmodulin regulates Cav3 T-type channels at their gating brake 

      Chemin, Jean; Taiakina, Valentina; Monteil, Arnaud; Piazza, Michael; Guan, Wendy; Stephens, Robert F.; Kitmitto, Ashraf; Pang, Zhiping P.; Dolphin, Annette C.; Perez-Reyes, Edward; Dieckmann, Thorsten; Guillemette, J. Guy; Spafford, J. David (American Society for Biochemistry and Molecular Biology, 2017-12-08)
      Calcium (Cav1 and Cav2) and sodium channels possess homologous CaM-binding motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a universal calcium sensor. Cav3 T-type channels, which serve ...
    • Solution Structure of Calmodulin Bound to the Target Peptide of Endothelial Nitric Oxide Synthase Phosphorylated at Thr495 

      Piazza, Michael; Taiakina, Valentina; Guillemette, Simon R.; Guillemette, J. Guy; Dieckmann, Thorsten (American Chemical Society, 2014-03-04)
      Nitric oxide synthase (NOS) plays a major role in a number of key physiological and pathological processes, and it is important to understand how this enzyme is regulated. The small acidic calcium binding protein, calmodulin ...
    • Structural Consequences of Calmodulin EF Hand Mutations 

      Piazza, Michael; Taiakina, Valentina; Dieckmann, Thorsten; Guillemette, J. Guy (American Chemical Society, 2017-02-21)
      Calmodulin (CaM) is a cytosolic Ca2+-binding protein that serves as a control element for many enzymes. It consists of two globular domains, each containing two EF hand pairs capable of binding Ca2+, joined by a flexible ...

      UWSpace

      University of Waterloo Library
      200 University Avenue West
      Waterloo, Ontario, Canada N2L 3G1
      519 888 4883

      All items in UWSpace are protected by copyright, with all rights reserved.

      DSpace software

      Service outages