Browsing Waterloo Research by Author "McNeil, Brooke"
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Ligand Specificity and Affinity in the Sulforhodamine B Binding RNA Aptamer
Piccolo, Kyle; McNeil, Brooke; Crouse, Jeff; Lim, Su Ji; Hopkins, W. Scott; Dieckmann, Thorsten (Elsevier Inc., 2020-07-18)Binding affinity and selectivity are critical properties of aptamers that must be optimized for any application. The sulforhodamine B binding RNA aptamer (SRB‐2) is a somewhat promiscuous aptamer that can bind ligands ...