Browsing Waterloo Research by Author "Dixon, Brian"
Now showing items 1-10 of 10
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CK-2 of rainbow trout (Oncorhynchus mykiss) has two differentially regulated alleles that encode a functional chemokine
Semple, Shawna L.; Eshaque, Shathi; Fujiki, Kazuhiro; Tang, Cynthia; Mitchell, Leslie; Bols, Niels C.; Dixon, Brian (Elsevier, 2018-04)Rainbow trout chemokine 2 (CK-2) is currently the only known CC chemokine to have a mucin stalk. Further analysis of the mucin stalk region revealed a second, related CC chemokine sequence, denoted here as CK-2.1. This ... -
Coinfection takes its toll: Sea lice override the protective effects of vaccination against a bacterial pathogen in Atlantic salmon
Figueroa, Carolina; Bustos, Paulina; Torrealba, Débora; Dixon, Brian; Soto, Carlos; Conejeros, Pablo; Gallardo, José A. (Springer Nature, 2017-12-19)Vaccination is considered crucial for disease prevention and fish health in the global salmon farming industry. Nevertheless, some aspects, such as the efficacy of vaccines, can be largely circumvented during natural ... -
Complete genome sequence of the fish pathogen Flavobacterium psychrophilum ATCC 49418T
Wu, Anson KK; Kropinski, Andrew M; Lumsden, John S.; Dixon, Brian; MacInnes, Janet I (BioMed Central, 2015-01-21)Flavobacterium psychrophilum is the causative agent of bacterial cold water disease and rainbow trout fry mortality syndrome in salmonid fishes and is associated with significant losses in the aquaculture industry. The ... -
Extracellular dsRNA induces a type I interferon response mediated via class A scavenger receptors in a novel Chinook salmon derived spleen cell line
Semple, Shawna L.; Vo, Nguyen T. K.; Poynter, Sarah J.; Li, M.; Heath, Daniel D.; DeWitte-Orr, Stephanie J.; Dixon, Brian (Elsevier, 2018-12-01)Despite increased global interest in Chinook salmon aquaculture, little is known of their viral immune defenses. This study describes the establishment and characterization of a continuous cell line derived from Chinook ... -
Impacts of Low Temperature on the Teleost Immune System
Abram, Quinn H.; Dixon, Brian; Katzenback, Barbara A. (Multidisciplinary Digital Publishing Institute, 2017-11-22)As poikilothermic vertebrates, fish can experience changes in water temperature, and hence body temperature, as a result of seasonal changes, migration, or efflux of large quantities of effluent into a body of water. ... -
Long-term implantation of acoustic transmitters induces chronic inflammatory cytokine expression in adult rainbow trout (Oncorhynchus mykiss)
Semple, Shawna L.; Mulder, Ingeborg M.; Rodriguez-Ramos, Tania; Power, Michael; Dixon, Brian (Elsevier, 2018-11-01)Telemetry transmitters are frequently used in studies of wild fish migration and behavior. Although the effects of surgically implanted transmitters on survival, tag retention, healing and growth have been studied, there ... -
Serum IgM, MH class IIβ genotype and respiratory burst activity do not differ between rainbow trout families displaying resistance or susceptibility to the coldwater pathogen, Flavobacterium psychrophilum
Semple, Shawna L.; Kellendonk, Calvin J.; Al-Hussinee, Lowia; MacInnes, Janet I.; Lumsden, John S.; Dixon, Brian (Elsevier, 2018-01-20)Flavobacterium psychrophilum, the causative agent of bacterial coldwater disease (BCWD) is a significant threat to global aquaculture. True to its name, BCWD tends to occur at temperatures between 8 and 12°C and presents ... -
Tapasin's protein interactions in the rainbow trout peptide-loading complex
Sever, Lital; Vo, Nguyen T. K.; Bols, Niels C.; Dixon, Brian (Elsevier, 2018-04-01)Major histocompatibility complex (MHC) class I receptors play a key role in the immune system by presenting non-self peptides to T cell lymphocytes. In humans, the assembly of the MHC class I with a peptide is mediated by ... -
Understanding acute stress-mediated immunity in teleost fish
Guo, Huming; Dixon, Brian (Elsevier, 2021-12)The abilities and ways in which organisms respond to stress have long been demonstrated to affect the immune response of the organism. In mammalian studies, researchers have observed that chronic/long-term stress has a ... -
Vaccines for finfish aquaculture: What do we need to know to make them work?
Dixon, Brian (Elsevier, 2012-08-08)Aquaculture still faces serious economic impacts due to the loss of animals to disease. A conservative estimate of 5% losses due to disease means that the finfish aquaculture industry loses over $1 billion annually on a ...