Browsing Waterloo Research by Author "Campbell, J. Larry"
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Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry
Liu, Chang; Le Blanc, J. C. Yves; Schneider, Bradley B.; Shields, Jefry; Federico, James J.; Zhang, Hui; Stroh, Justin G.; Kauffman, Gregory W.; Kung, Daniel W.; Ieritano, Christian; Shepherdson, Evan; Verbuyst, Mitch; Melo, Luke; Hasan, Moaraj; Naser, Dalia; Janiszewski, John S.; Hopkins, W. Scott; Campbell, J. Larry (American Chemical Society, 2017-02-22)The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially ... -
How Hot Are Your Ions in Differential Mobility Spectrometry?
Ieritano, Christian; Featherstone, Joshua; Haack, Alexander; Guna, Mircea; Campbell, J. Larry; Hopkins, W. Scott (American Chemical Society, 2020-01)Ions can experience significant field-induced heating in a differential mobility cell. To investigate this phenomenon, the fragmentation of several para-substituted benzylpyridinium “thermometer” ions (R = OMe, Me, F, Cl, ...