Browsing Physics and Astronomy by Author "Ha, Bae-Yeun"
Now showing items 1-4 of 4
-
Effects of molecular crowding and confinement on the spatial organization of a biopolymer
Jeon, Chanil; Jung, Youngkyun; Ha, Bae-Yeun (Royal Society of Chemistry, 2016-10-25)A chain molecule can be entropically collapsed in a crowded medium in a free or confined space. Here, we present a unified view of how molecular crowding collapses a flexible polymer in three distinct spaces: free, ... -
How are molecular crowding and the spatial organization of a biopolymer interrelated
Jeon, Chanil; Hyeon, Changbong; Jung, Youngkyun; Ha, Bae-Yeun (Royal Society of Chemistry, 2016-10-21)In a crowded cellular interior, dissolved biomolecules or crowders exert excluded volume effects on other biomolecules, which in turn control various processes including protein aggregation and chromosome organization. As ... -
Opposing effects of cationic antimicrobial peptides and divalent cations on bacterial lipopolysaccharides
Smart, Matthew; Rajagopal, Aruna; Liu, Wing-Ki; Ha, Bae-Yeun (American Physical Society, 2017-10-09)The permeability of the bacterial outer membrane, enclosing Gram-negative bacteria, depends on the interactions of the outer, lipopolysaccharide (LPS) layer, with surrounding ions and molecules. We present a coarse-grained ... -
A ring-polymer model shows how macromolecular crowding controls chromosome-arm organization in Escherichia coli
Jeon, Chanil; Jung, Youngkyun; Ha, Bae-Yeun (Nature Publishing Group, 2017-09-19)Macromolecular crowding influences various cellular processes such as macromolecular association and transcription, and is a key determinant of chromosome organization in bacteria. The entropy of crowders favors compaction ...