Now showing items 11-13 of 13
Parameterization of In Silico Oral Disposition Models: Focus on Pediatrics
(University of Waterloo, 2017-03-16)
Owing to their biologically relevant design, physiologically-based pharmacokinetic (PBPK) models require quantitative knowledge of organism anatomy and physiology to facilitate appropriate parameterization. Within such ...
Design, Synthesis and Biological Evaluation of Novel Adamantane Derivatives as Potential Treatments for Alzheimer’s Disease
(University of Waterloo, 2017-02-14)
Alzheimer’s disease (AD) is a complex, multifactorial, and rapidly neurodegenerative disorder characterized by cognitive impairment and progressive dementia. Its pathology was first characterized by Alois Alzheimer as “a ...
Synthesis and Characterisation of Chiral Nanomaterials and their Influence on Stem Cell Differentiation
(University of Waterloo, 2017-08-11)
Tissue engineering is a field related to regenerative medicine which aims at replacing or regenerating a patient’s tissue, usually using a combination of cells and a bioactive material which is designed to influence cell ...