Now showing items 1-3 of 3
Construction and Characterization of a Robust in vivo Technology for the Production of Superior DNA Vectors for Gene Therapy and Vaccination
(University of Waterloo, 2013-09-27)
Plasmid DNA (pDNA) vectors are the current conventional technology driving therapeutic gene transfer, whether for use toward mal/nonfunctional gene replacement, DNA vaccination, or production of therapeutic proteins in ...
Non-viral gemini surfactant-phospholipid nanoparticles for topical gene delivery to the retina
(University of Waterloo, 2013-01-29)
Glaucoma is a group of optic nerve degenerative diseases, which leads to gradual and permanent vision loss. Recent developments in the field of gene therapy have proposed increasingly promising treatments for glaucoma, in ...
Langmuir-Blodgett Monolayer Studies of Mixed Gemini Surfactant-Phospholipid Monolayers system for Gene Therapy Applications.
(University of Waterloo, 2015-10-23)
Gene delivery relies upon the encapsulation of a gene of interest, which is then ideally delivered to target cells. For gene therapy applications, viral vectors are the most efficient vectors currently being studied, ...