Now showing items 1-2 of 2
Evaluating the anti-leukemia activity of avocatin B
(University of Waterloo, 2015-01-15)
Acute myeloid leukemia (AML) is an aggressive malignant disease characterized by poor patient outcome and suboptimal front-line chemotherapy. To identify novel anti-AML compounds, a high-throughput screen of a natural ...
Glucopsychosine increases cytosolic calcium to induce calpain-mediated apoptosis of acute myeloid leukemia cells.
(University of Waterloo, 2014-08-20)
To identify novel anti-cancer agents, we created and screened a unique nutraceutical library for activity against acute myeloid leukemia (AML) cells. From this screen, we determined that glucopsychosine was selectively ...