Now showing items 1-4 of 4
Characterising changes in adhesion and enzyme activity related to drug resistance in colon cancer cells
(University of Waterloo, 2018-12-21)
Metastatic colorectal cancer is often fatal, and drug resistance to chemotherapeutic agents is one of the primary contributing factors to this lethality. Drug resistance arises from exposure to chemotherapies, and it can ...
Characterizing Changes in Dipeptidyl Peptidase IV/CD26 on Colon Carcinoma Cells in Response to Prostaglandin Treatment
(University of Waterloo, 2018-08-01)
Dipeptidyl peptidase IV (DPPIV) – also known as CD26 – is a multifunctional transmembrane protease found on the surface of most human cells, and shows variable expression between different types of cancer. DPPIV activity ...
Improving the delivery and immunogenicity of an inhalable CpG-ODN DNA vaccine by bio-adhesive gemini nanoparticles in neonatal chickens
(University of Waterloo, 2018-01-05)
Cytosine-phosphodiester-guanine oligodeoxynucleotides (CpG-ODN) are nucleotide sequence motifs found in the bacterial genome that activate the mammalian innate immune response and have been found to boost humoral immunity ...
The impact of prescription medication cost coverage on optimal adherence to Hypertension and Diabetes Mellitus oral medications
(University of Waterloo, 2018-02-26)
Background: It can be difficult for patients who do not have prescription medication cost coverage to adhere to their medications. No previous study has examined the time-trend and impact of absence of coverage on adherence ...