Now showing items 1-6 of 6
Physiologically-based pharmacokinetic model for ciprofloxacin in children with complicated urinary tract infection
In a recent multicenter population pharmacokinetic study of ciprofloxacin administered to children suffering from complicated urinary tract infection (cUTI), the apparent volume of distribution (V) and total plasma clearance ...
Exploring the role of teams and technology in patients' medication decision making
We know little about how electronic health records (EHRs) should be designed to help patients, pharmacists, and physicians participate in interprofessional shared decision making. We used a qualitative approach to understand ...
Communicating health information in primary care: a multidisciplinary exploration of patient, pharmacist, and physician decision-making
(University of Waterloo, 2019-06-27)
Research has yet to clearly define how health care professionals’ (HCPs) use and sharing of information influences how health decisions are made, both independently and collaboratively. Similarly, the manner in which ...
Cell Density-Dependent Changes in the Localization of the CD26 Protein in Colorectal Cancer Cells in Response to Flavonoid Treatment
(University of Waterloo, 2019-05-24)
Colorectal cancer is the 3rd most common cancer worldwide and this rate of incidence is largely attributable to lifestyle factors such as the diet. A group of plant secondary metabolites called flavonoids has been found ...
Health and Economic Impact of Treatment-based Strategies on Chronic Hepatitis B in Ontario
(University of Waterloo, 2019-08-23)
Background/Aim: The lives of about 257 million people in the world are being affected by chronic hepatitis B (CHB), and this contagious disease is gradually pushing them closer to the edge of death caused by cirrhosis and ...
Characterization of Bacteriophage λ Displaying Epidermal Growth Factor in the Uptake, Infiltration and Formation of HT29 Spheroids
(University of Waterloo, 2019-07-31)
Solid tumours are characterized by a complex structure comprised of extracellular matrix, neoplastic cells and stromal cells, each presenting a barrier to conventional anticancer chemotherapy as well as carrier-mediated ...