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Implant delivering hydroxychloroquine attenuates vaginal T lymphocyte activation and inflammation
Evidence suggests that women who are naturally resistant to HIV infection exhibit low baseline immune activation at the female genital tract (FGT). This “immune quiescent” state is associated with lower expression of T-cell ...
Design and development of pH-responsive polyurethane membranes for intravaginal release of nanomedicines
The objective of this study was to develop and characterize a novel intravaginal membrane platform for pH-triggered release of nanoparticles (NPs), which is essential for efficient intravaginal delivery of certain effective ...
Dynamic mechanical behaviour of nanoparticle loaded biodegradable PVA films for vaginal drug delivery
(Sage Publishing, 2018-03-01)
In this study, we investigated the viscoelastic and mechanical behaviour of polyvinyl alcohol films formulated along with carrageenan, plasticizing agents (polyethylene glycol and glycerol), and when loaded with nanoparticles ...