Browsing Pharmacy by Subject "NMDA"
Now showing items 1-2 of 2
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GPCR and RTK Regulation in Neurons: The Impact of Stress on GPCR and RTK signalling and Crosstalk
(University of Waterloo, 2020-04-14)Crosstalk between receptors allows for the integration of diverse and complex signalling pathways. Transactivation is a form of crosstalk between G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). ... -
Investigating the neuroprotective potential of short-term 5-HT7 receptor activation against neuronal excitotoxicity
(University of Waterloo, 2015-10-05)The pathophysiology of cerebral ischemia or acute ischemic stroke involves what is called neuronal "excitotoxicity", where an initial failure in intracellular energy metabolism causes excessive pre-synaptic glutamate release ...