Optometry and Vision Science: Recent submissions
Now showing items 21-40 of 246
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Changes in corneal thickness in keratoconic eyes with variation in scleral contact lens central clearance
(University of Waterloo, 2021-08-30)Purpose: There has been a resurgence of scleral lens wear, particularly for patients with corneal ectasia, such as keratoconus. This method of lens correction provides good visual acuity for these individuals and is often ... -
Electrophysiological measures of optic nerve function
(University of Waterloo, 2021-08-26)The contribution of retinal ganglion cells (RGCs) to human electroretinograms (ERGs) is known, but that of chicken (Gallus gallus domesticus) is not clear. This project seeks to determine the effect of RGC dysfunction on ... -
Effect of vision-based treatments on visual acuity and motor function in children with amblyopia
(University of Waterloo, 2021-08-19)Purpose: To investigate existing as well as novel vision-based treatments in children with amblyopia and determine the utility of motor function as a potential outcome measure. Methods: Three experiments were conducted. ... -
Development of an in vitro eye model to better represent in vivo physiological conditions
(University of Waterloo, 2021-06-23)Purpose The purpose of this thesis was to optimize a novel in vitro blink model, the OcuBlink, to best mimic the physiological characteristics of the human eye. By improving this in vitro model, the results from in vitro ... -
Non-invasive brain stimulation of the primary visual cortex of healthy adults and individuals with amblyopia
(University of Waterloo, 2021-05-03)Introduction: Amblyopia is a neurological condition that affects the visual cortex and causes visual deficits, typically in one eye. Recovery from amblyopia requires significant visual cortex neuroplasticity to allow for ... -
An investigation into the motivations, influences and expectations of students studying optometry in Canada and the United States of America
(University of Waterloo, 2021-04-01)Purpose: To investigate and compare the motivations, influences and expectations of Doctor of Optometry students studying in Canada and the United States of America. Methods: A survey was created, piloted, and conducted ... -
Automated Cataract Grading using Smartphone Images
(University of Waterloo, 2021-02-02)A cataract is an age-related eye disease and is one of the leading ophthalmological public health problems in developed and developing countries. Early detection of cataracts is necessary to preserve sight and prevent the ... -
Explainable AI for retinal OCT diagnosis
(University of Waterloo, 2021-01-20)Artificial intelligence methods such as deep learning are leading to great progress in complex tasks that are usually associated with human intelligence and experience. Deep learning models have matched if not bettered ... -
Retinal Structure and Function in Typical Children and Young Adults
(University of Waterloo, 2021-01-20)Purpose. Children with visual impairment may be referred for ERG and OCT testing to aid in diagnosis and monitoring, particularly those with suspected retinal diseases. To establish if a result is abnormal, knowledge of ... -
In Vitro Release of Inflammatory Cytokines from Contact Lens Materials
(University of Waterloo, 2020-12-22)The upregulation of inflammatory mediators in the tear film during contact lens wear indicates that lens wear may induce an inflammatory response on the ocular surface. Previous research has investigated the relationship ... -
Ocular Perfusion Pressure in Spaceflight-Associated Neuro-Ocular Syndrome
(University of Waterloo, 2020-10-26)Purpose: Spaceflight associated neuro-ocular syndrome (SANS) is considered by the National Aeronautics and Space Administration (NASA) as one of the most significant barriers to long term space exploration (Larkin, 2018). ... -
Neural modulation of the human visual cortex
(University of Waterloo, 2020-09-30)Neuroplasticity is a phenomenon that refers to the brain’s ability to reorganize, strengthen, and form neural connections, a process that becomes increasingly more difficult with age. Gamma amino-butyric acid (GABA), the ... -
Game play in virtual reality driving simulation involving head-mounted display and comparison to desktop display
(Springer, 2019-11-28)Previous studies have reported the effect of driving simulator games on simulator sickness and eye symptoms experienced by users; however, empirical results regarding the game experience using commercial virtual reality ... -
Deep Generative Modeling Based Retinal Image Analysis
(University of Waterloo, 2020-06-16)In the recent past, deep learning algorithms have been widely used in retinal image analysis (fundus and OCT) to perform tasks like segmentation and classification. But to build robust and highly efficient deep learning ... -
Development of sports-specific classification for Paralympic skiers with visual impairment
(University of Waterloo, 2020-05-28)Introduction: The Paralympic Games are not only a platform for athletes with disabilities to achieve their dreams, but the Games also play a major role in changing societal attitudes towards people with disabilities and ... -
Studies on the Optimization of Neuropeptides Detection in the Human Tear Film
(University of Waterloo, 2020-05-13)Introduction: Dry Eye Disease (DED) stems from a disruption of the homeostasis of the tear film (TF), a thin layer of fluid covering the ocular surface. The TF consists of numerous constituents that include proteins, ... -
Comparison of meibomian gland dropout using two infrared imaging devices
(Elsevier, 2018-11-07)Purpose To measure the degree of meibomian gland (MG) dropout in the lower eyelid determined by analysis of images obtained from the LipiView II (LVII) and the Keratograph 5M (K5M). Methods The inferior eyelid of each ... -
Tear evaporation rates: What does the literature tell us?
(Elsevier, 2017-12-24)Purpose A previous literature review reported tear evaporation rates (TERs) from studies conducted on rabbits and humans between 1941 and 2003. Closer examination of the presented data revealed inaccuracies in the reporting ... -
Corneal sensitivity after ocular surgery
(Wolters Kluwer, 2019-07-01)The cornea is densely innervated with free nerve endings to provide a high level of sensitivity to foreign bodies or noxious substances. They also provide trophic support to the tissues of the cornea and facilitate their ... -
Interaction of Tear Inflammatory Markers with Contact Lens Materials
(University of Waterloo, 2020-01-28)Biomaterials are natural or synthetic materials that come into contact with biological tissue. Contact lenses are the most commonly used biomaterials, being worn by an estimated 140 million people worldwide. While contact ...