Browsing Optometry and Vision Science by Issue Date
Now showing items 61-80 of 246
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Viability Profile of ex vivo Corneal Epithelial Cell Samples
(University of Waterloo, 2011-10-28)The corneal epithelium is a vital tissue which must retain its integrity to preserve vision and protect against harmful bacterial infections and other insults. Corneal disease represents the second most common cause of ... -
Contact lens physical properties and lipid deposition in a novel characterized artificial tear solution
(Molecular Vision, 2011-12-24)Purpose: To characterize various properties of a physiologically-relevant artificial tear solution (ATS) containing a range of tear film components within a complex salt solution, and to measure contact lens parameters and ... -
Acetic and Acrylic Acid Molecular Imprinted Model Silicone Hydrogel Materials for Ciprofloxacin-HCl Delivery
(Multidisciplinary Digital Publishing Institute, 2012-01-02)Contact lenses, as an alternative drug delivery vehicle for the eye compared to eye drops, are desirable due to potential advantages in dosing regimen, bioavailability and patient tolerance/compliance. The challenge has ... -
Modeling In Vitro Lipid Deposition on Silicone Hydrogel and Conventional Hydrogel Contact Lens Materials
(University of Waterloo, 2012-01-12)Purpose: To examine the variables that influence lipid deposition on conventional and silicone hydrogel contact lens materials and to build a physiologically relevant in vitro model of lipid deposition on contact lenses. ... -
Type 2 diabetes mellitus and the prevalence of age-related cataract in a clinic population.
(University of Waterloo, 2012-01-24)Purpose: The prevalence of diabetes (DM) is increasing globally with type 2 diabetes (T2DM) being primarily responsible for this alarming trend. Age and DM have been associated with an increased prevalence of AR cataract ... -
Composition of incubation solution impacts in vitro protein uptake to silicone hydrogel contact lenses
(Molecular Vision, 2012-02-04)Purpose: To determine the impact of incubation solution composition on protein deposition to silicone hydrogel (SH) contact lenses using a simplistic and a complex model of the tear film. Methods: Three SH materials – ... -
Correlation of visually evoked intrinsic optical signals and electroretinograms recorded from chicken retina with a combined functional optical coherence tomography and electroretinography system
(Society of Photo Optical Instrumentation Engineers, 2012-02-08)Visually evoked fast intrinsic optical signals (IOSs) were recorded for the first time in vivo from all layers of healthy chicken retina by using a combined functional optical coherence tomography (fOCT) and electroretinography ... -
Contact lens fitting characteristics and comfort with silicone hydrogel lenses
(University of Waterloo, 2012-02-24)Purpose To examine soft contact lens fitting characteristics using anterior segment imaging techniques and comfort. The specific aims of each chapter are as follows: Chapter 2: To calibrate the new ZEISS VisanteTM ... -
Effect of heterophoria type and myopia on accommodative and vergence responses during sustained near activity in children
(Elsevier, 2012-03-15)The influence of phoria-type and myopia on changes to vergence and accommodation during prolonged near-task was examined in 53 children. Participants were classified into phoria and refractive categories based on near ... -
Release of Ciprofloxacin-HCl and Dexamethasone Phosphate by Hyaluronic Acid Containing Silicone Polymers
(Multidisciplinary Digital Publishing Institute, 2012-04-19)The purpose of this study was to determine the effect of the covalent incorporation of hyaluronic acid (HA) into conventional hydrogel and hydrogels containing silicone as models for contact lens materials on the uptake ... -
Impact of in vitro Tear Film Composition on Lysozyme Deposition and Denaturation
(University of Waterloo, 2012-08-31)Purpose To study the impact of lactoferrin and lipids on the kinetic deposition and denaturation of lysozyme on contact lens materials. Methods The contact lenses investigated in this thesis included two silicone ... -
Psychophysical and Clinical Investigations of Ocular Discomfort
(University of Waterloo, 2012-09-26)Purpose To investigate ocular surface sensations, specifically ocular discomfort using psychophysical and clinical techniques. The measurement of discomfort on the ocular surface has been limited to the use of traditional ... -
Retinal degeneration in and in vivo electroretinography measurements of Smoky Joe Chickens
(University of Waterloo, 2012-09-28)Inherited retinal degenerative diseases can affect various components of the retina leading to blindness. Five different mutant strains of chicken have been studied extensively as potential models for inherited retinal ... -
An investigation of interocular suppression with a global motion task
(University of Waterloo, 2012-10-31)Abstract Purpose: Interocular inhibitory interactions appear to underlie the establishment of ocular dominance. The inhibitory effect leads to suppression of the non dominant eye in certain conditions. While these ... -
Investigations on the Reptilian Spectacle
(University of Waterloo, 2012-12-12)The eyes of snakes and most geckos, as well as a number of other disparate squamate taxa, are shielded beneath a layer of transparent integument referred to as the “reptilian spectacle.” Derived from the embryonic fusion ... -
Insights to Using Contact Lenses for Drug Delivery
(Omics International, 2013)There has been considerable interest in the potential application of contact lenses for ocular drug delivery. This short communication provides an overview of the challenges faced by delivering drugs using contact lenses, ... -
Historical overview of imaging the meibomian glands
(Elsevier, 2013-01)Growing knowledge of the role of the meibomian glands in dry eye disease and contact lens discomfort has resulted in a surge of interest in visualizing these glands within the eyelids. This manuscript provides an overview ... -
Retinal Blood Flow and Vascular Reactivity in Chronic Smokers
(University of Waterloo, 2013-02-25)Purpose To investigate the impact of cigarrete smoking in a group of otherwise healthy young individuals on: 1) Retinal blood flow using Doppler based SD-OCT, 2) Retinal vascular reactivity using a gas sequencer to ... -
Inhibition of Defocus-Induced Myopia in Chickens
(Association for Research in Vision and Ophthalmology, 2013-04-12)Purpose.: To determine the effect of wearing a lens with a unique peripheral optical design on the development and progression of defocus-induced myopia in newly hatched chickens.Methods.: Eighty-five newly hatched chickens ... -
Patient compliance with contemporary contact lenses: Impact on successful contact lens wear
(University of Waterloo, 2013-04-15)Purpose: Contact lens (CL) materials, modalities of wear and replacement, and care systems have changed considerably since the early studies of CL compliance were first conducted. Silicone hydrogel (SiHy) and daily disposable ...