Browsing Optometry and Vision Science by Issue Date
Now showing items 21-40 of 246
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Optimization of Sweep Visually Evoked Potential (sVEP) in Adults
(University of Waterloo, 2008-05-01)Purpose and hypothesis: The purpose of this study was to optimize and standardize the following parameters of sweep Visually Evoked Potential (sVEP) in adults: criteria for fitting the regression line to estimate threshold, ... -
CLINICAL AND ANALYTICAL STUDIES IN POSTMENOPAUSAL WOMEN SYMPTOMATIC OF DRY EYE
(University of Waterloo, 2008-05-22)Introduction Menopause which is defined as a permanent physiological, or natural, cessation of menstrual cycle, plays an important role in the development of ocular surface dryness symptoms and there is an increased ... -
Central and Peripheral Cornea and Corneal Epithelium Characterized Using Optical Coherence Tomography and Confocal Microscopy
(University of Waterloo, 2008-05-22)Abstract Both in the closed and open eye state the superior limbus is covered by the upper lid. This region is of physiological interest and clinical importance because in chronic hypoxia, neovascularization of the ... -
Impact of Wavefront-Guided Laser in situ Keratomileusis on Monochromatic Higher Order Aberrations and Vision
(University of Waterloo, 2008-07-04)Wavefront-guided (WFG) laser in situ keratomileusis (LASIK) differs from conventional surgery by applying a refined algorithm for tissue removal, based on information from preoperative wavefront aberration data. Since the ... -
Retinal Vascular Reactivity to Incremental Hyperoxia During Isocapnia
(University of Waterloo, 2008-07-07)PURPOSE: Systemic hyperoxia has been induced using inspired gases in many studies to investigate vascular reactivity in the retinal vasculature. Technical limitations in the past resulted in inadequate control of systemic ... -
Ultraviolet B and blue light - induced phototoxic effects on retinal pigment epithelium using in vitro assays
(University of Waterloo, 2008-09-12)It is well known that ultraviolet (UV) B (280-315 nm) and blue light (400-500 nm) radiation can produce phototoxic lesions in the neural retina and the retinal pigment epithelium (RPE). In the first section of this thesis, ... -
Fish (Oreochromis niloticus) as a Model of Refractive Error Development
(University of Waterloo, 2009-01-13)Myopia is a common ocular condition worldwide and the mechanism of myopia is still not clear. A number of animal models of myopia and refractive error development have been proposed. The fact that form deprivation myopia ... -
Understanding the mechanisms of flicker defined form processing
(University of Waterloo, 2009-01-15)Flicker defined form (FDF) is a temporally-dependent illusion created by the counterphase flicker of randomly positioned element dots, that preferentially stimulates the magnocellular system. Previous studies have found ... -
Mitochondrial Function and Optical Properties of the Crystalline Lens
(University of Waterloo, 2009-01-15)The crystalline lens is a unique cellular organ that performs metabolic processes while maintaining optical functionality. Mitochondria play a vital role in providing the cell with the energy necessary for these metabolic ... -
Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products
(University of Waterloo, 2009-04-27)The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty ... -
Protein Deposition and Bacterial Adhesion to Conventional and Silicone Hydrogel Contact Lens Materials
(University of Waterloo, 2009-04-27)Introduction Contact lenses suffer from the same problems of deposition that other biomaterials exhibit, being rapidly coated with a variety of proteins, lipids and mucins. The first event observed at the interface between ... -
Development of Novel Techniques for Measuring Bulbar Conjunctival Red Blood Cell Velocity, Oximetry and Redness
(University of Waterloo, 2009-04-29)Introduction The ocular surface provides a unique opportunity to study hemodynamics since the vessels can be visualized directly, without treatment and non-invasively. The availability of instruments to measure various ... -
Colour Vision Test for Railway Dispatchers
(University of Waterloo, 2009-04-29)Introduction Colour codes are used extensively in railways to convey specific information governing movement of trains and equipment on the track. One such task is the railway traffic control display that uses colour coded ... -
Sjogren's Syndrome: A Clinical and Biochemical Analysis
(University of Waterloo, 2009-04-30)Sjogren’s syndrome (SS) is a systemic autoimmune disease that presents to eye care practitioners with the hallmark symptom of “dry eye.” Stratifying dry eye patients as Sjogren’s positive or negative is a critical ... -
Retinal and Optic Nerve Head Vascular Reactivity in Primary Open Angle Glaucoma
(University of Waterloo, 2009-05-14)The global aim of this thesis was to assess retinal vascular reactivity in glaucoma patients using a standardised hypercapnic stimulus. There is a suggestion of disturbance in the regulation of retinal and optic nerve head ... -
Binocular Adaptation to +2 D Lenses in Myopic and Emmetropic Children:
(Wolters Kluwer, 2009-06)Purpose. To compare vergence adaptation to +2 D addition lenses in myopic and emmetropic children and to evaluate the influence of the accommodative-vergence crosslink (AC/A ratio) on this adaptation. Methods. Nine ... -
Studies of Visual Attention
(University of Waterloo, 2009-06-22)Aim The experiment proposed to study the effect of sustained visual attention in an effective visual field of 40 degrees, in cued and uncued conditions with different set-sizes. Methods The participants had a normal ... -
A Computational Model for Predicting Visual Acuity from Wavefront Aberration Measurements
(University of Waterloo, 2009-09-14)The main purpose of this thesis is to create and validate a visual acuity model with experimentally obtained aberrations of human eyes. The other motivation is to come up with a methodology to objectively predict the ... -
The Effects of 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride (ML-7) on the Lens During Avian Accommodation In Situ
(University of Waterloo, 2009-12-17)A previous study in chickens revealed that myosin light chain kinase (MLCK), f actin, and myosin are found on the crystalline lens. Their polygonal arrangement at the posterior surface resembles a muscle tissue, which ... -
Protein sorption to contact lenses and intraocular lenses
(University of Waterloo, 2009-12-22)Purpose: To locate protein sorption on the surface and inside the matrix of soft contact lens materials and intraocular lenses (IOL). Methods: The proteins albumin and lysozyme were investigated as they are highly ...