Now showing items 208-227 of 233

    • Tear evaporation rates: What does the literature tell us? 

      Wong, Stephanie; Murphy, Paul J.; Jones, Lyndon W. (Elsevier, 2017-12-24)
      Purpose A previous literature review reported tear evaporation rates (TERs) from studies conducted on rabbits and humans between 1941 and 2003. Closer examination of the presented data revealed inaccuracies in the reporting ...
    • Tear exchange and contact lenses: A review 

      Muntz, Alex; Subbaraman, Lakshman N.; Sorbara, Luigina; Jones, Lyndon W. (Elsevier, 2015-01)
      Tear exchange beneath a contact lens facilitates ongoing fluid replenishment between the ocular surface and the lens. This exchange is considerably lower during the wear of soft lenses compared with rigid lenses. As a ...
    • The tear ferning test: a simple clinical technique to evaluate the ocular tear film 

      Masmali, Ali M.; Purslow, Christine; Murphy, Paul J. (Wiley, 2014-08-20)
      A healthy tear film is very important for many major functions of the ocular surface. Dry eye disease is a significant clinical problem that needs to be solved but the poor correlation between clinical signs and reported ...
    • The TFOS Dry Eye Workshop II: Executive Summary 

      Craig, Jennifer P.; Nelson, J. Daniel; Azar, Dimitri T.; Belmonte, Carlos; Bron, Anthony J.; Chauhan, Sunil K.; de Paiva, Cintia S.; Gomes, José A.P.; Hammitt, Katherine M.; Jones, Lyndon W.; Nichols, Jason J.; Nichols, Kelly K.; Novack, Gary D.; Stapleton, Fiona; Willcox, Mark D. P.; Wolffsohn, James S.; Sullivan, David A. (Elsevier, 2017-08-07)
      This article presents an Executive Summary of the conclusions and recommendations of the 10-chapter TFOS DEWS II report. The entire TFOS DEWS II report was published in the July 2017 issue of The Ocular Surface. A downloadable ...
    • The TFOS International Workshop on Contact Lens Discomfort: Executive Summary 

      Nichols, Jason J.; Willcox, Mark D. P.; Bron, Anthony J.; Belmonte, Carlos; Ciolino, Joseph B.; Craig, Jennifer P.; Dogru, Murat; Foulks, Gary N.; Jones, Lyndon W.; Nelson, J. Daniel; Nichols, Kelly K.; Purslow, Christine; Schaumberg, Debra A.; Stapleton, Fiona; Sullivan, David A. (Association for Research in Vision and Ophthalmology, 2013-10-18)
      Contact lens discomfort (CLD) is a frequently experienced problem, with most estimates suggesting that up to half of contact lens wearers experience this problem with some frequency or magnitude. This condition impacts ...
    • The TFOS International Workshop on Contact Lens Discomfort: Introduction 

      Nichols, Jason J.; Jones, Lyndon W.; Nelson, J. Daniel; Stapleton, Fiona; Sullivan, David A.; Willcox, Mark D. P. (Association for Research in Vision and Ophthalmology, 2013-10-18)
      For many years, the contact lens field had focused on safety associated with contact lens wear—and for good reason, given the lack of understanding of the risk factors and etiology of serious complications such as microbial ...
    • The TFOS International Workshop on Contact Lens Discomfort: Report of the Contact Lens Interactions With the Ocular Surface and Adnexa Subcommittee 

      Efron, Nathan; Jones, Lyndon W.; Bron, Anthony J.; Knop, Erich; Arita, Reiko; Barabino, Stefano; McDermott, Alison M.; Villani, Edoardo; Willcox, Mark D. P.; Markoulli, Maria (Association for Research in Vision and Ophthalmology, 2013-10-18)
      The report of this subcommittee concerns the impact of contact lenses (CLs) on the ocular surface, with a particular emphasis on CL discomfort (CLD). We define the ocular surface, its regional anatomy, and the physiological ...
    • The TFOS International Workshop on Contact Lens Discomfort: Report of the Contact Lens Materials, Design, and Care Subcommittee 

      Jones, Lyndon W.; Brennan, Noel A.; González-Méijome, José; Lally, John; Maldonado-Codina, Carole; Schmidt, Tannin A.; Subbaraman, Lakshman; Young, Graeme; Nichols, Jason J. (Association for Research in Vision and Ophthalmology, 2013-10-18)
      Examining the role of the contact lens material, design, and the care system is fundamental to understanding contact lens discomfort (CLD). However, a systematic review that tries to determine the governing factors is ...
    • Time Course of Dichoptic Masking in Normals and Suppression in Amblyopes 

      Zhou, Jiawei; McNeill, Suzanne; Babu, Raiju Jacob; Baker, Daniel H.; Bobier, William; Hess, Robert F. (Association of Research in Vision and Ophthalmology, 2014-07)
      Purpose.: To better understand the relationship between dichoptic masking in normal vision and suppression in amblyopia we address three questions: First, what is the time course of dichoptic masking in normals and amblyopes? ...
    • Topical anaesthetic use prior to rigid gas permeable contact lens fitting 

      Gill, Felicity; Murphy, Paul J.; Purslow, Christine (Elsevier, 2017-07-11)
      Purpose To investigate effect of topical anaesthetic (TA) during gas permeable (GP) contact lens (CL) fitting on subjective and objective measures of patient anxiety. Methods 47 subjects (mean ± sd age = 26.9 ± 4.9 ...
    • Total Retinal Blood Flow and Retinal Oxygen Saturation in the Major Retinal Vessels of Healthy Participants 

      Oteng-Amoako, Afua (University of Waterloo, 2013-09-27)
      Introduction: Oxygen delivery, or utilization, is a function of retinal blood flow and blood oxygen saturation. The retinal pigment epithelium (RPE), in particular, has been shown to have the highest levels of metabolic ...
    • Towards point-of-care detection of polymicrobial infections: Rapid colorimetric response using a portable spectrophotometer 

      Verma, Mohit S.; Tsuji, Jackson M.; Hall, Brad; Chen, Paul Z.; Forrest, James; Jones, Lyndon W.; Gu, Frank X. (Elsevier, 2016-09)
      Infectious diseases spread rapidly because current diagnostic methods are slow, expensive, and require technical expertise. Biosensors have recently been used as devices that can be deployed at the point-of-care for rapid ...
    • Toxicity of Ophthalmic Solutions, Benzalkonium Chloride and UV Radiation on Human Corneal Epithelial Cells in vitro 

      Xu, Manlong (University of Waterloo, 2015-06-12)
      The purpose of this work was to develop a sensitive in vitro method for ocular toxicity testing; and to use this method to assess the individual and combined effects of ophthalmic solutions, benzalkonium chloride (BAK), ...
    • Type 2 diabetes mellitus and the prevalence of age-related cataract in a clinic population. 

      Machan, Carolyn M (University of Waterloo, 2012-01-24)
      Purpose: The prevalence of diabetes (DM) is increasing globally with type 2 diabetes (T2DM) being primarily responsible for this alarming trend. Age and DM have been associated with an increased prevalence of AR cataract ...
    • Ultraviolet B and blue light - induced phototoxic effects on retinal pigment epithelium using in vitro assays 

      Youn, Hyun-Yi (University of Waterloo, 2008-09-12)
      It is well known that ultraviolet (UV) B (280-315 nm) and blue light (400-500 nm) radiation can produce phototoxic lesions in the neural retina and the retinal pigment epithelium (RPE). In the first section of this thesis, ...
    • Understanding the mechanisms of flicker defined form processing 

      Goren, Deborah (University of Waterloo, 2009-01-15)
      Flicker defined form (FDF) is a temporally-dependent illusion created by the counterphase flicker of randomly positioned element dots, that preferentially stimulates the magnocellular system. Previous studies have found ...
    • Understanding the Mechanisms Underlying Brain Plasticity in Adult Humans 

      Abuleil, Dania (University of Waterloo, 2017-09-22)
      Purpose: The human brain changes signi cantly with age. The plasticity of the visual cortex is thought to decrease into adulthood while childrens' brains are highly plastic. This change in plasticity is thought to be due, ...
    • Understanding the sensory and motor behavior of accommodation in progressive myopic children 

      Labhishetty, Vivek (University of Waterloo, 2017-09-27)
      Introduction: Accommodation and vergence, in unison, help in maintaining a clear and single binocular vision, a linchpin for normal vision development. Under natural viewing conditions, accommodation and vergence systems ...
    • Unmasking the linear behaviour of slow motor adaptation to prolonged convergence 

      Erkelens, Ian; Thompson, Benjamin; Bobier, William; Munoz, Doug (Wiley, 2016-06)
      Adaptation to changing environmental demands is central to maintaining optimal motor system function. Current theories suggest that adaptation in both the skeletal-motor and oculomotor systems involves a combination of ...
    • Uptake and release of preservatives from soft contact lens materials 

      Yee, Alan (University of Waterloo, 2022-01-13)
      Purpose: The purpose of this thesis was to examine the uptake and release of myristamidopropyl dimethylamine (MAPD) and polyhexamethylene biguanide (PHMB) from soft contact lens material using various in vitro models to ...

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