Now showing items 21-40 of 250

    • Automated Cataract Grading using Smartphone Images 

      Nasir zonouzi, Mona (University of Waterloo, 2021-02-02)
      A cataract is an age-related eye disease and is one of the leading ophthalmological public health problems in developed and developing countries. Early detection of cataracts is necessary to preserve sight and prevent the ...
    • Automated Segmentation of Retinal Optical Coherence Tomography Images 

      Roy, Priyanka (University of Waterloo, 2018-08-21)
      Aim. Optical Coherence Tomography (OCT) is a fast and non-invasive medical imaging technique which helps in the investigation of each individual retinal layer structure. For early detection of retinal diseases and the study ...
    • Bifocals in children with Down syndrome (BiDS) 

      Nandakumar, Krithika (University of Waterloo, 2010-07-28)
      Down syndrome (DS) is the most common genetic cause of mental challenge in individuals and is associated with many ocular disorders. One of these anomalies which is frequently present in this population is reduced accommodation ...
    • Binocular Adaptation to +2 D Lenses in Myopic and Emmetropic Children: 

      Sreenivasan, Vidhyapriya; Irving, Elizabeth; Bobier, William (Wolters Kluwer, 2009-06)
      Purpose. To compare vergence adaptation to +2 D addition lenses in myopic and emmetropic children and to evaluate the influence of the accommodative-vergence crosslink (AC/A ratio) on this adaptation. Methods. Nine ...
    • Binocular adaptation to near addition lenses in emmetropic adults 

      Sreenivasan, Vidhyapriya; Irving, Elizabeth; Bobier, William (Elsevier, 2008-05)
      Near addition lenses are prescribed to pre-presbyopic individuals for treatment of binocular motor problems such as convergence excess and to control the progression of myopia. To date, no investigation has looked at the ...
    • Binocular treatment of amblyopia using videogames (BRAVO): study protocol for a randomised controlled trial 

      Guo, Cindy X.; Thompson, Benjamin; Babu, Raiju Jacob; Black, Joanna M.; Bobier, William; Lam, Carly S.Y.; Dai, Shaun; Gao, Tina Y.; Hess, Robert F.; Jenkins, Michelle; Jiang, Yannan; Kowal, Lionel; Parag, Varsha; South, Jayshree; Staffieri, Sandra Elfride; Walker, Natalie; Wadham, Angela (BioMed Central, 2016-10-18)
      Amblyopia is a common neurodevelopmental disorder of vision that is characterised by visual impairment in one eye and compromised binocular visual function. Existing evidence-based treatments for children include patching ...
    • Binocular vision and fixational eye movements 

      Nallour Raveendran, Rajkumar (University of Waterloo, 2017-07-19)
      Introduction In observers with amblyopia, abnormal patterns of amblyopic eye (AME) fixational eye movements (FEM) have been associated with monocular (reduced amblyopic eye visual acuity) and binocular sensory deficits ...

      Lu, Fenghe (University of Waterloo, 2006)
      <strong>Purpose:</strong> Although orthokeratology (non-surgical corneal reshaping, Corneal Refractive Therapy, CRT®) has been used for almost a half century, contemporary CRT's outcomes and mechanisms still require ...
    • The blood compatibility challenge. Part 3: Material associated activation of blood cascades and cells 

      Gorbet, Maud; Sperling, Claudia; Maitz, Manfred; Siedleck, Christopher A.; Werner, Carsten; Sefton, Michael V. (Elsevier, 2019-08)
      Following protein adsorption/activation which is the first step after the contact of material surfaces and whole blood (part 2), fibrinogen is converted to fibrin and platelets become activated and assembled in the form ...
    • Branching and size of CTAB-coated gold nanostars control the colorimetric detection of bacteria 

      Verma, Mohit S.; Chen, Paul Z.; Jones, Lyndon W.; Gu, Frank X. (Royal Society of Chemistry, 2014)
      Rapid detection of pathogenic bacteria is challenging because conventional methods require long incubation times. Nanoparticles have the potential to detect pathogens before they can cause an infection. Gold nanostars have ...
    • Calibration and validation the Dynamic Photorefraction System (DPRS) 

      Labhishetty, Vivek (University of Waterloo, 2014-09-25)
      Introduction: Our group has been measuring accommodation in myopic children. The instrument of choice has been the Power Refractor (Multichannel Systems). However, this instrumentation is no longer supported and runs on ...
    • Can current models of accommodation and vergence predict accommodative behavior in myopic children? 

      Sreenivasan, Vidhyapriya; Irving, Elizabeth; Bobier, William (Elsevier, 2014-08)
      Investigations into the progression of myopia in children have long considered the role of accommodation as a cause and solution. Myopic children show high levels of accommodative adaptation, coupled with accommodative lag ...
    • Can kynurenic acid cause myelin loss in chicken optic nerves? 

      Gurdita, Akshay (University of Waterloo, 2017-09-27)
      Kynurenic acid (KYNA) is one of many kynurenine intermediate products in the tryptophan metabolism pathway and has been shown to have neuro-activity. Previous work revealed that prolonged infusion of a high dose of KYNA ...
    • Cell death and proliferation characteristics of the retina after optic nerve section in chickens 

      Chong, Stacey (University of Waterloo, 2013-09-27)
      Optic nerve section (ONS) is an experimental model for damage of the optic nerve associated with diseases such as glaucoma and optic neuritis. Damage to the optic nerve causes loss of retinal ganglion cells that are ...
    • Cellular changes at the lid margin 

      Muntz, Alex (University of Waterloo, 2017-11-28)
      PURPOSE: The hypothesis underlying this thesis is that CL wear, lid wiper epitheliopathy (LWE), and symptoms of dryness and discomfort may be manifest as cellular changes of the lid marginal epithelium, as a result of ...
    • Central and Peripheral Cornea and Corneal Epithelium Characterized Using Optical Coherence Tomography and Confocal Microscopy 

      Ghasemi, Nasrin (University of Waterloo, 2008-05-22)
      Abstract Both in the closed and open eye state the superior limbus is covered by the upper lid. This region is of physiological interest and clinical importance because in chronic hypoxia, neovascularization of the ...
    • Central Visual Field Assessment in Late Stage Glaucoma 

      Balian, Carmen (University of Waterloo, 2006)
      Glaucoma is defined as a progressive optic neuropathy, characterized by loss of visual function and often associated with high intra-ocular pressure. Testing the patients' visual function with Standard Automated Perimetry ...
    • Changes in corneal thickness in keratoconic eyes with variation in scleral contact lens central clearance 

      Carter, Kirsten (University of Waterloo, 2021-08-30)
      Purpose: There has been a resurgence of scleral lens wear, particularly for patients with corneal ectasia, such as keratoconus. This method of lens correction provides good visual acuity for these individuals and is often ...
    • Characterization of Lipid Deposition on Contact Lenses 

      Qiao, Han (University of Waterloo, 2017-08-30)
      The purpose of this thesis was to evaluate the influence of lipid deposition on silicone hydrogel contact lens materials and to construct an in vitro platform to further explore the effect of lipid interaction with contact ...

      Srinivasan, Sruthi (University of Waterloo, 2008-05-22)
      Introduction Menopause which is defined as a permanent physiological, or natural, cessation of menstrual cycle, plays an important role in the development of ocular surface dryness symptoms and there is an increased ...


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