Browsing Chemistry by Supervisor "Pawliszyn, Janusz"
Now showing items 1-20 of 21
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Application of matrix compatible solid phase microextraction (SPME) coatings for the analysis in complex food matrices
(University of Waterloo, 2020-01-06)In recent years, studies regarding food analysis have increased due to the globalization of food trade as well as concerns about the safety and traceability of food commodities. In this regard, the field of food analysis ... -
Application of Solid Phase Microextraction for Lipid Analysis and Lipidomics
(University of Waterloo, 2016-01-29)Although the latest advancements in lipid analysis technology provide an excellent opportunity for the comprehensive study of lipidome, fulfilling the analytical requirements at the desired quality is still a major ... -
Automated High-throughput Analysis of Multi-class Multi-residue Pharmaceutical Drugs in Animal Tissue Using Solid Phase Microextraction
(University of Waterloo, 2020-05-06)The use of veterinary pharmaceuticals in today´s intensive farming of food-producing animals is essential for the humane treatment of animals and as well as for the prevention of outbreaks of infectious diseases. Improper ... -
Chemical biopsy via solid phase microextraction: strategies and applications for in vivo brain studies
(University of Waterloo, 2020-08-19)Adequate and quantitative observation of neurochemical phenomena is instrumental in guiding efforts towards a better understanding of the mechanisms underlying brain functions. Although a plethora of highly focused mechanistic ... -
Development and Application of Solid-Phase Microextraction Probe Electrospray Ionization
(University of Waterloo, 2020-12-21)Ambient ionization mass spectrometry (AIMS) is a category of mass spectrometry (MS) techniques originally characterized as using ambient ionization sources to analyze samples with little to no sample preparation and no ... -
Development and application of SPME technologies for the rapid sampling and analysis of anthropogenic compounds in the environment
(University of Waterloo, 2017-04-27)Due to the wide spread use of pharmaceuticals in both human and animal populations, the contamination of surface waters resulting from the outflow of waste water treatment facilities is of growing concern. Conventional ... -
Development and optimization of coated blade spray - mass spectrometry for bioanalytical and clinical applications
(University of Waterloo, 2018-08-23)Bioanalysis is a sub-discipline of analytical chemistry that focuses on the identification and quantification of small and large molecules (e.g. metabolites and proteins) present in biological sample matrices (e.g. blood, ... -
Development and Study of the Microfluidic Open Interface Coupled with Solid-phase Microextraction for Rapid Analysis
(University of Waterloo, 2022-09-28)Analytical chemistry mainly aims to identify and quantify analytes in matrices of interest. Analytical chemistry is an indispensable part of chemistry (and other scientific fields) because identification and quantification ... -
Development of Field Portable Solid Phase Microextraction Samplers for Performing On-site Environmental Analysis
(University of Waterloo, 2018-04-30)Since being introduced in 1989 solid phase microextraction (SPME) techniques have continually evolved from within the analytical chemistry community due in large part to their clean, portable and easy to handle design. It ... -
Development of Needle Trap Devices for Particle Entrapment
(University of Waterloo, 2022-05-25)The importance of studying particle-bound components in aerosol samples has been highlighted during the COVID-19 pandemic, when people tried to stop the spread of droplet-bound viruses by wearing face masks. While the ... -
Development of Solid Phase Microextraction Methodologies for the Determination of Anthropogenic Contaminants from Fatty Food Matrices
(University of Waterloo, 2019-09-03)Anthropogenic contaminants have been on the rise worldwide due to global industrialization. The world is now faced with the consequences of the pollution caused by the exposure of man-made chemicals in the environment. ... -
Developments and applications of solid phase microextraction (SPME) coupled to direct analysis in real time (DART) and approaches towards small volume analysis
(University of Waterloo, 2019-08-21)Solid phase microextraction (SPME) has been rapidly developing since its invention in 1990. Due to a flexible design and the ability to implement various extractive coatings, SPME has found use in numerous applications. ... -
Exploration of the suitability of coated blade spray for rapid analysis of pesticides in agricultural commodities and byproducts
(University of Waterloo, 2020-09-03)The multiresidue analysis of pesticides in domestic and imported agricultural products is completed on hundreds of thousands of samples yearly by regulatory agencies in the United States, Canada, and Europe. Currently, ... -
Fundamentals of SPME extraction of tissue and plasma: experimental and in-silico approaches
(University of Waterloo, 2021-12-15)Over the last three decades, solid-phase microextraction (SPME) has continuously evolved and received recognition as a useful tool in various scientific fields. Notable applications have been published including environmental ... -
Insight into Quantitation of Solid-phase Microextraction
(University of Waterloo, 2016-07-21)Solid-phase microextraction (SPME) is a well-known sampling and sample preparation technique used for a wide variety of analytical applications. As there are various complex processes taking place at the time of extraction ... -
INVESTIGATION OF PROTEIN-DRUG INTERACTION USING CAPILLARY ISOELECTRIC FOCUSING WITH WHOLE COLUMN IMAGING DETECTION AND SPECTROSCOPIC TECHNIQUES
(University of Waterloo, 2009-03-26)In this work, the possibilities of understanding protein-drug interactions and the possible modes of action of the drug have been was explored using capillary isoelectric focusing (CIEF) and spectroscopic techniques. The ... -
New strategies for analysis of particulate loaded water
(University of Waterloo, 2016-05-16)This thesis describes the application of thin film solid phase microextraction (TF-SPME) for monitoring of time weighted average (TWA) concentrations and for investigating partitioning of UV filters and biocides in aquatic ... -
Solid Phase Microextraction as a Sample Preparation Tool for Targeted and Untargeted Analysis of Biological Matrices
(University of Waterloo, 2017-09-27)Successful determination of small molecules in complex biological systems requires implementation of robust analytical methodologies able to provide reliable information in a cost-effective and efficient manner. Solid phase ... -
Solid phase microextraction: a versatile technique for lipid analysis
(University of Waterloo, 2023-04-26)Extensive multidisciplinary research and improvements to instrumentation and workflows are continuously enabling new insights into the role of lipids in health and disease. As with other metabolites, the accurate analysis ... -
Strategies for the Direct Coupling of Solid Phase Microextraction to Mass Spectrometry
(University of Waterloo, 2017-09-27)In recent years, advances in direct sample to mass spectrometry (MS) techniques have allowed for the application of these methods towards quantitative analysis in complex matrices such as biofluids and tissue. However, the ...