Browsing Chemistry by Issue Date
Now showing items 21-40 of 836
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Biochemistry in Bacterioferritin
(University of Waterloo, 2006)Bacterioferritin, an iron storage protein having a 24-subunit quaternary structure, was used as a model for the study of host-guest interactions and guest encapsulation, making use of its spherical cage-like structure. ... -
Multiple Substituent Effects on the Rate Constants for N(2)-N(3) Restricted Rotation of cis-1,3-Diphenyltriazenes
(University of Waterloo, 2006)Triazenes represent an interesting class of organic photochromic materials based on cis-trans isomerization around a nitrogen-containing double bond, and of potential use in optical memory devices. One structural property ... -
Development and characterization of a laminar aerosol flow tube
(AIP, 2006-03)We have developed a new laminar aerosol flow tube (AFT) to study transformations such as ice nucleation, deliquescence, and efflorescence in model atmospheric aerosols. The apparatus consists of four sections which can be ... -
Development of New Carbon-Carbon Bond-Forming Strategies: Formation and Reactivity of sp³-gem-Organodimetallic Palladium(II)/MRn Alkane Intermediates (MRn=Dialkylalumino, Trialkylstannyl)
(University of Waterloo, 2006-12-01)Investigation of the catalytic formation, reactivity and synthetic scope of sp³-gem-organodimetallic palladio(II)/main group metal (main group metal = tributylstannyl, dialkylalumino) alkane species has been carried out. ... -
BIOCOMPATIBLE SOLID PHASE MICROEXTRACTION
(University of Waterloo, 2006-12-12)Today’s solid phase microextraction (SPME) is a well known technique that combines knowledge from different fields in an attractive, efficient, and economic way. The development of SPME has seen huge growth since its ... -
Role of NOS-like proteins found in bacteria
(University of Waterloo, 2007-01-22)Nitric oxide (•NO) is a molecule with diverse biological effects involved in both signaling and defense mechanisms in mammalian systems. The production of •NO is catalyzed from L-Arginine by a family of enzymes known as ... -
Effects of Myristoylation on the Structure and Stability of Hisactophilin
(University of Waterloo, 2007-01-23)Hisactophilin is a histidine rich, actin binding protein from Dictyostelium discoideum. The structure of Hisactophilin, an all-beta protein, is typical of the beta-trefoil superfamily of proteins. In addition, hisactophilin ... -
Monitoring Chain Dynamics by Luminescence Using a Long-Lived Ruthenium Dye
(University of Waterloo, 2007-01-24)The purpose of this research project was to determine the feasibility of labelling a water-soluble polymer with a water-soluble dye and quencher. The water-soluble dye chosen was bis-(2,2-bipyridine)-ruthenium(II) -5-am ... -
Investigations into Intracellular Thiols of Biological Importance
(University of Waterloo, 2007-02-01)The presence of thiols in living systems is critical for the maintenance of cellular redox homeostasis, the maintenance of protein thiol-disulfide ratios and the protection of cells from reactive oxygen species. In addition ... -
Synthesis of Inhibitors of Steroid Sulfatase and Towards the Synthesis of a Chiral Electrophilic Fluorinating Reagent
(University of Waterloo, 2007-02-02)Steroid sulfatase (STS) catalyzes the desulfation of sulfated steroids such as estrone sulfate to the corresponding steroid such as estrone. Inhibitors of STS are believed to have potential for treating estrogen-dependent ... -
Synthesis and Characterization of Oil-soluble Dispersants
(University of Waterloo, 2007-02-19)Oil-soluble dispersants are some of the most important additives used by the oil industry. Their function is to reduce the aggregation of carbonaceous deposits produced during the normal operation of the engine. This project ... -
Comparison of Ion Mobility Spectrometry and Gas Chromatography with Dry Electrolytic Conductivity Detection for the Determination of Polychlorinated Biphenyls in Humus-Rich Soil
(University of Waterloo, 2007-02-21)Ion mobility spectroscopy (IMS) has been showen to provide fast on-site analysis of coarse sandy soil for the determination of polychlorinated biphenyls (PCBs). However the presence of humus results in instrument foaling ... -
Thermoelectric properties of new transition metal arsenides and antimonides
(University of Waterloo, 2007-04-17)The main focus of this work is on exploratory investigation of thermoelectric (TE) materials. Thermoelectric devices are solid-state devices that convert thermal energy from a temperature gradient into electrical energy ... -
High-resolution laboratory spectroscopy of transient metal-containing molecules
(University of Waterloo, 2007-05-14)Ten gaseous transient metal-containing molecules have been synthesized and studied by high resolution spectroscopy. Transient molecules are molecules with a short lifetime, and they play an important role in chemistry ... -
Development of a Cost-Effective and Consumable-Free Interface for Comprehensive Two-Dimensional Gas Chromatography (GC×GC)
(University of Waterloo, 2007-05-23)The biggest limitation to conventional gas chromatography (GC) is limited peak capacity, making the analysis of complex mixtures a difficult or even impossible task. Comprehensive two-dimensional gas chromatography (GC×GC) ... -
Design, Synthesis and Characterization of a Series of Self-assembling Polypeptides
(University of Waterloo, 2007-05-24)A series of polypeptides with well-defined sequences, (Asp3Phe1)n, (Asp2Phe1)n, (Asp1Phe1)n, (Asp1Phe2)n, and (Asp1Phe3)n, containing the hydrophilic amino acid, aspartic acid (Asp) and the hydrophobic amino acid, phenylalanine ... -
Preparing and Tuning the Reactivity of Palladium Carbenes and an Unusual Catalytic Isomerization of Diphenylcyclopropanes
(University of Waterloo, 2007-09-26)The preparation of palladium carbene intermediates from diphenylketene is proposed. Experiments to trap these intermediates with alkenes have been conducted and optimized, with cyclopropanes being prepared in up to 69% ... -
The Thermochemistry of Protonated and Sodiated Clusters Investigated via High-Pressure Mass Spectrometry
(University of Waterloo, 2007-09-27)High-pressure mass spectrometry has been employed to investigate hydrogen and sodium bound ion-molecule complexes in the gas phase. Insight into the structure and reactivity of ion-molecule complexes has been gained by ... -
Membrane Interactions of Streptococcus agalactiae's CAMP factor
(University of Waterloo, 2007-09-27)CAMP factor is an extracellular pore-forming toxin secreted by the group B streptococci Streptococcus agalactiae. In conjunction with the action of sphingomyelinase secreted by Staphylococcus aureus, which converts membrane ... -
Equilibrium and kinetic folding studies of two YchN-like proteins: the Tm0979 dimer and the Mth1491 trimer
(University of Waterloo, 2007-09-28)Proper folding of a protein to its native state is critical for the protein to be fully functional under biological conditions. Understanding protein folding and protein folding evolution within the same structural family ...