Browsing Chemistry by Author "c9423e9f-0291-482b-b3e3-bec877410124"

Now showing items 1-3 of 3

Investigations on the Oligomerization of Pyolysin, a Cholesterol-Dependent Cytolysin

Pokrajac, Lisa A. (University of Waterloo, 2011-01-25)

The bacterial toxin pyolysin (PLO) is a member of the family of Cholesterol-Dependent Cytolysins, which form large, oligomeric pores in cholesterol-containing membranes. The general CDC structure has an elongated shape and ...
Oligomerization and hemolytic properties of the C-terminal domain of pyolysin, a cholesterol-dependent cytolysin

Pokrajac, Lisa A.; Harris, J. Robin; Sarraf, Naghmeh S.; Palmer, Michael (NRC Research Press, 2013-04)

Pyolysin (PLO) belongs to the homologous family of the cholesterol-dependent cytolysins (CDCs), which bind to cell membranes containing cholesterol to form oligomeric pores of large size. The CDC monomer structure consists ...
Partial oligomerization of pyolysin induced by a disulfide-tethered mutant

Pokrajac, Lisa A.; Baik, Clara; Harris, J. Robin; Sarraf, Naghmeh S.; Palmer, Michael (NRC Research Press, 2012-12)

The bacterial toxin pyolysin (PLO) belongs to the family of cholesterol-dependent cytolysins (CDCs), which form large, ring-shaped oligomeric pores in cholesterol-containing membranes. Monomeric CDC molecules have a structure ...