Browsing Chemistry by Author "Wang, Feng"
Now showing items 1-17 of 17
-
Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles
Zhang, Xu; Wang, Feng; Liu, Biwu; Kelly, Erin Y.; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2014-01-28)Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules to harness their molecular recognition function. ... -
Citrate inhibition of cisplatin reaction with DNA studied using fluorescently labeled oligonucleotides: implication for selectivity towards guanine
Wang, Feng; Huang, Po-Jung Jimmy; Liu, Juewen (Royal Society of Chemistry, 2013-10-21)The reaction between cisplatin and DNA is conveniently studied using fluorescently labeled oligonucleotides and gel electrophoresis; as an example of application, the inhibition of this reaction by citrate is demonstrated, ... -
A Cleavable Molecular Beacon for Hg2+ Detection based on Phosphorothioate RNA Modifications
Huang, Po-Jung Jimmy; Wang, Feng; Liu, Juewen (American Chemical Society, 2015-06-10)Mercury is a highly toxic heavy metal, and detection of Hg2+ by biosensors has attracted extensive research interest in the past decade. In particular, a number of DNA-based sensing strategies have been developed. Well-known ... -
Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection
Liang, Hao; Jiang, Shuhui; Yuan, Qipeng; Li, Guofeng; Wang, Feng; Zhang, Zijie; Liu, Juewen (Royal Society of Chemistry, 2016-03-21)Preserving enzyme activity and promoting synergistic activity via co-localization of multiple enzymes are key topics in bionanotechnology, materials science, and analytical chemistry. This study reports a facile method for ... -
Driving Adsorbed Gold Nanoparticle Assembly by Merging Lipid Gel/Fluid Interfaces
Wang, Feng; Curry, Dennis E.; Liu, Juewen (American Chemical Society, 2015-11-23)Surface forces between inorganic nanoparticles and lipid bilayer is of great relevance to biophysics, medicine, and nanobiotechnology. Adsorbed nanoparticles may influence the fluidity of the underlying lipids, which may ... -
Evaporation induced wrinkling of graphene oxide at the nanoparticle interface
Wang, Feng; Liu, Juewen (Royal Society of Chemistry, 2015-01-21)With the thickness of only a single atomic layer, graphene displays many interesting surface properties. A general observation is that wrinkles are formed on graphene oxide (GO) when it is dried in the presence of adsorbed ... -
Liposome Supported Metal Oxide Nanoparticles: Interaction Mechanism, Light Controlled Content Release and Intracellular Delivery
Wang, Feng; Liu, Juewen (Wiley, 2014-05-26)Zwitterionic phosphotydylcholine liposomes stably adsorb a number of metal oxide nanoparticles via its phosphate group. This is different from physisorption and fusion with SiO2. The hybrid materials can be internalized ... -
Liposome/Graphene Oxide Interaction Studied by Isothermal Titration Calorimetry
Huang, Po-Jung Jimmy; Wang, Feng; Liu, Juewen (American Chemical Society, 2015-03-15)The interaction between graphene oxide (GO) and lipid bilayers is important for fundamental surface science and many applications. In this work, isothermal titration calorimetry (ITC), cryo-TEM, and fluorescence spectroscopy ... -
Nanodiamond decorated liposomes as highly biocompatible delivery vehicles and a comparison with carbon nanotubes and graphene oxide
Wang, Feng; Liu, Juewen (Royal Society of Chemistry, 2013-12-21)Studying interactions between nano-carbons and lipid membranes is important for multiplexed drug delivery, device fabrication and for understanding toxicity. Herein, we report that nanodiamond (ND, sp3 carbon) forms a ... -
Orthogonal Adsorption Onto Nano-Graphene Oxide Using Different Intermolecular Forces for Multiplexed Delivery
Wang, Feng; Liu, Biwu; Ip, Alexander C-F.; Liu, Juewen (Wiley, 2013-05-31)Nano-graphene oxide can adsorb both doxorubicin and zwitterionic dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes in an orthogonal and non-competing manner with high capacities based on different surface and intermolecular ... -
Parts-per-Million of Polyethylene Glycol as a Non-Interfering Blocking Agent for Homogeneous Biosensor Development
Liu, Biwu; Huang, Po-Jung Jimmy; Zhang, Xu; Wang, Feng; Pautler, Rachel; Ip, Alexander C-F.; Liu, Juewen (American Chemical Society, 2013-11-05)Many homogeneous assays are complicated by the adsorption of probe molecules by the surface of reaction vessels, which are often made of polypropylene or polystyrene-based plastics. To solve this problem, many protein and ... -
Platinated DNA oligonucleotides: new probes forming ultrastable conjugates with graphene oxide
Wang, Feng; Liu, Juewen (Royal Society of Chemistry, 2014-06-21)Metal containing polymers have expanded the property of polymers by involving covalently associated metal complexes. DNA is a special block copolymer. While metal ions are known to influence DNA, little is explored on its ... -
Profiling Metal Oxides with Lipids: Magnetic Liposomal Nanoparticles Displaying DNA and Proteins
Wang, Feng; Zhang, Xiaohan; Liu, Yibo; Lin, Zhi Yuan (William); Liu, Biwu; Liu, Juewen (Wiley, 2016-09-19)Metal oxides include many important materials with various surface properties. For biomedical and analytical applications, it is desirable to engineer their biocompatible interfaces. Herein, a phosphocholine liposome (DOPC) ... -
Rationally Designed Nucleobase and Nucleotide Coordinated Nanoparticles for Selective DNA Adsorption and Detection
Wang, Feng; Liu, Biwu; Huang, Po-Jung Jimmy; Liu, Juewen (American Chemical Society, 2013-12-17)Nanomaterials for DNA adsorption are useful for sequence-specific DNA detection. Current materials for DNA adsorption employ electrostatic attraction, hydrophobic interaction, or π–π stacking, none of which can achieve ... -
Self-healable and reversible liposome leakage by citrate-capped gold nanoparticles probing initial adsorption/desorption induced lipid phase transition
Wang, Feng; Liu, Juewen (Royal Society of Chemistry, 2015-10-14)We herein report that the adsorption/desorption of citrate-capped gold nanoparticles (AuNPs) transiently causes leakage in fluid phase DOPC liposomes, while the liposomes do not leak with AuNPs capped with mercaptopropionic ... -
Tandem DNAzymes for mRNA cleavage: choice of enzyme, metal ions and the antisense effect
Wang, Feng; Saran, Runjhun; Liu, Juewen (Elsevier, 2015-04-01)The concept of DNAzyme-based gene silencing via mRNA cleavage was proposed over twenty years ago. A number of studies regarding intracellular gene silencing have been reported as well. However, questions have been raised ... -
Tandem Phosphorothioate Modifications for DNA Adsorption Strength and Polarity Control on Gold Nanoparticles
Zhou, Wenhu; Wang, Feng; Ding, Jinsong; Liu, Juewen (American Chemical Society, 2014-09-10)Unmodified DNA was recently used to functionalize gold nanoparticles via DNA base adsorption. Compared to thiolated DNA, however, the application of unmodified DNA is limited by the lack of sequence generality, adsorption ...