Browsing Chemistry by Author "Servos, Mark. R."
Now showing items 1-20 of 33
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A 30-Year Study of Impacts, Recovery, and Development of Critical Effect Sizes for Endocrine Disruption in White Sucker (Catostomus commersonii) Exposed to Bleached-Kraft Pulp Mill Effluent at Jackfish Bay, Ontario, Canada
Ussery, Erin J.; McMaster, Mark E.; Servos, Mark. R.; Miller, David H.; Munkittrick, Kelly R. (Frontiers, 2021-04-22)Jackfish Bay is an isolated bay on the north shore of Lake Superior, Canada that has received effluent from a large bleached-kraft pulp mill since the 1940s. Studies conducted in the late 1980s found evidence of reductions ... -
Adsorption of DNA Oligonucleotides by Titanium Dioxide Nanoparticles
Zhang, Xu; Wang, Feng; Liu, Biwu; Kelly, Erin Y.; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2014-01-28)Titanium dioxide (TiO2) or titania shows great promise in detoxification and drug delivery. To reach its full potential, it is important to interface TiO2 with biomolecules to harness their molecular recognition function. ... -
An Assessment of the Spatial and Temporal Variability of Biological Responses to Municipal Wastewater Effluent in Rainbow Darter (Etheostoma caeruleum) Collected along an Urban Gradient
Fuzzen, Meghan; Bragg, Leslie M.; Tetreault, Gerald R.; Bahamonde, Paulina; Tanna, Rajiv N.; Bennett, Charles J.; McMaster, Mark E.; Servos, Mark R. (PLOS, 2016-10-24)Municipal wastewater effluent (MWWE) and its constituents, such as chemicals of emerging concern, pose a potential threat to the sustainability of fish populations by disrupting key endocrine functions in aquatic organisms. ... -
Biological responses in fish exposed to municipal wastewater treatment plant effluent in situ
Tetreault, G .R.; Kleywegt, S.; Marjan, P.; Bragg, L.; Arlos, M.; Fuzzen, Meghan; Smith, B.; Moon, T.; Massarsky, A.; Metcalfe, C.; Oakes, K.; McMaster, M. E.; Servos, Mark. R. (IWA Publishing, 2021-04-16)Effluents from municipal wastewater treatment plants (MWTPs) are complex mixtures of chemicals including endocrine-disrupting compounds (EDCs) and 17α-ethynylestradiol (EE2). The objective of this study was to evaluate ... -
Characterizing Transcriptional Networks in Male Rainbow Darter (Etheostoma caeruleum) that Regulate Testis Development over a Complete Reproductive Cycle
Bahamonde, Paulina; McMaster, Mark E.; Servos, Mark R.; Martyniuk, Christopher J.; Munkittrick, Kelly R. (PLOS, 2016-11-18)Intersex is a condition that has been associated with exposure to sewage effluents in male rainbow darter (Etheostoma caeruleum). To better understand changes in the transcriptome that are associated with intersex, we ... -
Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age
Arts, Eric; Brown, Stephen; Bulir, David; Charles, Trevor C.; DeGroot, Christopher T.; Delatolla, Robert; Desaulniers, Jean-Paul; Edwards, Elizabeth A.; Fuzzen, Meghan; Gilbride, Kimberly; Gilchrist, Jodi; Goodridge, Lawrence; Graber, Tyson E.; Habash, Marc; Jüni, Peter; Kirkwood, Andrea; Knockleby, James; Kyle, Christopher; Landgraff, Chrystal; Mangat, Chand; Manuel, Douglas G.; McKay, R. Michael; Mejia, Edgard; Mloszewska, Aleksandra; Ormeci, Banu; Oswald, Claire; Payne, Sarah Jane; Peng, Hui; Peterson, Shelley; Poon, Art F. Y.; Servos, Mark. R.; Simmons, Denina; Sun, Jianxian; Yang, Minqing; Ybazeta, Gustavo (Research Square, 2022-03-15)Wastewater-based surveillance of SARS-CoV-2 RNA has been implemented at building, neighbourhood, and city levels throughout the world. Implementation strategies and analysis methods differ, but they all aim to provide rapid ... -
Contrasting physiological responses between invasive sea lamprey and non-target bluegill in response to acute lampricide exposure
Lawrence, M. J.; Mitrovic, D.; Foubister, D.; Bragg, L. M.; Sutherby, Josh; Docker, M. F.; Servos, Mark. R.; Wilkie, M. P.; Jeffries, K. M. (Elsevier, 2021-08-01)Control of invasive sea lamprey (Petromyzon marinus) in the Laurentian Great Lakes of North America uses lampricides, which consist of 3-trifluoromethyl-4-nitrophenol (TFM) and niclosamide. Lampricides are thought to inhibit ... -
Effect of Background Water Matrices on Pharmaceutical and Personal Care Product Removal by UV-LED/TiO2
Fattahi, Azar; Jaciw-Zurakowsky, Ivana; Srikanthan, Nivetha; Bragg, Leslie M.; Liang, Robert; Zhou, Norman Y.; Servos, Mark. R.; Arlos, Maricor Jane (Multidisciplinary Digital Publishing Institute, 2021-04-30)In this study, we evaluated the effectiveness of UV-LED-irradiated TiO2 in removing 24 commonly detected PPCPs in two water matrices (municipal wastewater effluent and Suwannee River NOM–synthetic water) and compared their ... -
Effects of Polyethylene Glycol on DNA Adsorption and Hybridization on Gold Nanoparticles and Graphene Oxide
Zhang, Xu; Huang, Po-Jung Jimmy; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-10-09)Understanding the interface between DNA and nanomaterials is crucial for rational design and optimization of biosensors and drug delivery systems. For detection and delivery into cells, where high concentrations of cellular ... -
Emergence and Spread of the SARS-CoV-2 Omicron Variant in Alberta Communities Revealed by Wastewater Monitoring
Hubert, Casey R. J.; Acosta, Nicole; Waddell, Barbara J.; Hasing, Maria E.; Qiu, Yuanyuan; Fuzzen, Meghan; Harper, Nathanael B. J.; Bautista, María A.; Gao, Tiejun; Papparis, Chloe; Doorn, Jean V.; Du, Kristine; Xiang, Kevin; Chan, Leslie; Vivas, Laura; Pradhan, Puja; McCalder, Janine; Low, Kashtin; England, Whitney E.; Kuzma, Darina; Conly, John; Ryan, M. Cathryn; Achari, Gopal; Hu, Jia; Cabaj, Jason L.; Sikora, Chris; Svenson, Larry; Zelyas, Nathan; Servos, Mark. R.; Meddings, Jon; Hrudey, Steve E.; Frankowski, Kevin; Parkins, Michael D.; Pang, Xiaoli; Lee, Bonita E. (medRxiv, 2022-10-03)Wastewater monitoring of SARS-CoV-2 allows for early detection and monitoring of COVID-19 burden in communities and can track specific variants of concern. Targeted assays enabled relative proportions of SARS-CoV-2 Omicron ... -
Endocrine Disruptor Impacts on Fish From Chile: The Influence of Wastewaters
Barra, Ricardo O.; Chiang, Gustavo; Saavedra, Maria Fernanda; Orrego, Rodrigo; Servos, Mark. R.; Hewitt, L. Mark; McMaster, Mark E.; Bahamonde, Paulina; Tucca Díaz, Felipe; Munkittrick, Kelly R. (Frontiers, 2021-03-25)Industrial wastewaters and urban discharges contain complex mixtures of chemicals capable of impacting reproductive performance in freshwater fish, called endocrine-disrupting compounds (EDCs). In Chile, the issue was ... -
Evaluating the Sampling Design of a Long-Term Community-Based Estuary Monitoring Program
Kidd, Jess; Boudreau, Monica; Bailey, Robert C.; van den Heuvel, Michael R.; Servos, Mark. R.; Courtenay, Simon C. (Multidisciplinary Digital Publishing Institute, 2021-08-02)Community-based monitoring programs (CBMPs) are a cost-effective option to collect the long-term data required to effectively monitor estuaries. Data quality concerns have caused some CBMP datasets, which could fill knowledge ... -
Fast pH-assisted functionalization of silver nanoparticles with monothiolated DNA
Zhang, Xu; Servos, Mark R.; Liu, Juewen (Royal Society of Chemistry, 2012-10-18)Attaching monothiolated DNA to silver nanoparticles has been achieved at pH 3.0 in 30 minutes and difficulties associated with DNA attachment to AgNPs at neutral pH have been revealed by studying DNA adsorption kinetics. -
Gold nanoparticles as dehydrogenase mimicking nanozymes for estradiol degradation
Zhang, Zijie; Bragg, Leslie M.; Servos, Mark R.; Liu, Juewen (Elsevier, 2019-09)Nanozyme catalysis has been mainly focused on a few chromogenic and fluorogenic substrates, while environmentally and biologically important compounds need to be tested to advance the field. In this work, we studied oxidation ... -
High Throughput Sequencing of MicroRNA in Rainbow Trout Plasma, Mucus, and Surrounding Water Following Acute Stress
Ikert, Heather; Lynch, Michael D. J.; Doxey, Andrew; Giesy, John P.; Servos, Mark. R.; Katzenback, Barbara A.; Craig, Paul M. (Frontiers, 2021-01-13)Circulating plasma microRNAs (miRNAs) are well established as biomarkers of several diseases in humans and have recently been used as indicators of environmental exposures in fish. However, the role of plasma miRNAs in ... -
Impacts on Metabolism and Gill Physiology of Darter Species (Etheostoma spp.) That Are Attributed to Wastewater Effluent in the Grand River
Hodgson, Rhiannon; Bragg, Leslie M.; Dhiyebi, Hadi A.; Servos, Mark. R.; Craig, Paul M. (Multidisciplinary Digital Publishing Institute, 2020-11-25)The effluent from municipal wastewater treatment plants is a major point source of contamination in Canadian waterways. The improvement of effluent quality to reduce contaminants, such as pharmaceuticals and personal care ... -
In vivo microsampling to capture the elusive exposome
Bessonneau, Vincent; Ings, Jennifer Sophia; McMaster, Mark; Smith, Richard; Bragg, Leslie M.; Servos, Mark R.; Pawliszyn, Janusz (Nature Publishing Group, 2017-03-07)Loss and/or degradation of small molecules during sampling, sample transportation and storage can adversely impact biological interpretation of metabolomics data. In this study, we performed in vivo sampling using solid-phase ... -
Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route
Zhang, Xu; Servos, Mark R.; Liu, Juewen (American Chemical Society, 2012-05-02)The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark works in nanobiotechnology. This conjugate chemistry is typically performed using a salt-aging protocol where, in the presence of an ... -
Instantaneous Attachment of an Ultrahigh Density of Nonthiolated DNA to Gold Nanoparticles and Its Applications
Zhang, Xu; Dave, Neeshma; Servos, Mark R.; Liu, Juewen; Liu, Biwu (American Chemical Society, 2012-12-11)The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within the emerging field of nanobiotechnology. Many novel ... -
Multiple Stressors in the Environment: The Effects of Exposure to an Antidepressant (Venlafaxine) and Increased Temperature on Zebrafish Metabolism
Mehdi, Hossein; Bragg, Leslie M.; Servos, Mark R.; Craig, Paul M. (Multidisciplinary Digital Publishing Institute, 2019-11-19)Aquatic organisms are continuously exposed to multiple environmental stressors working cumulatively to alter ecosystems. Wastewater-dominated environments are often riddled by a myriad of stressors, such as chemical and ...