Now showing items 1-10 of 29
DNA Adsorption by ZnO Nanoparticles near Its Solubility Limit: Implications for DNA Fluorescence Quenching and DNAzyme Activity Assays
(American Chemical Society, 2016-06-07)
Zinc oxide (ZnO) is a highly important material, and Zn2+ is a key metal ion in biology. ZnO and Zn2+ interconvert via dissolution and hydrolysis/condensation. In this work, we explore their interactions with DNA, which ...
Parallel Polyadenine Duplex Formation at Low pH Facilitates DNA Conjugation onto Gold Nanoparticles
(American Chemical Society, 2016-11-15)
DNA-functionalized gold nanoparticles (AuNPs) have been extensively used in sensing, drug delivery, and materials science. A key step is to attach DNA to AuNPs, forming a stable and functional conjugate. Although the ...
Reversible gating of ion transport through DNA-functionalized carbon nanotube membranes
(Royal Society of Chemistry, 2017-01-03)
Carbon nanotubes (CNTs) can be used to create unique fluidic systems for studying ion transport in nanochannels due to their well-defined geometry, atomically smooth and chemically inert surface, and similarity to transmembrane ...
Comparison of Graphene Oxide and Reduced Graphene Oxide for DNA Adsorption and Sensing
(American Chemical Society, 2016-10-18)
Fluorescently labeled DNA adsorbed on graphene oxide (GO) is a well-established sensing platform for detecting a diverse range of analytes. GO is a loosely defined material and its oxygen content may vary depending on the ...
Boosting the oxidase mimicking activity of nanoceria by fluoride capping: rivaling protein enzymes and ultrasensitive F- detection
(Royal Society of Chemistry, 2016-07-28)
Nanomaterial-based enzyme mimics (nanozymes) are currently a new forefront of chemical research. However, the application of nanozymes is limited by their low catalytic activity and low turnover numbers. Cerium dioxide ...
Profiling Metal Oxides with Lipids: Magnetic Liposomal Nanoparticles Displaying DNA and Proteins
Metal oxides include many important materials with various surface properties. For biomedical and analytical applications, it is desirable to engineer their biocompatible interfaces. Herein, a phosphocholine liposome (DOPC) ...
Oxidation Level-Dependent Zwitterionic Liposome Adsorption and Rupture by Graphene-based Materials and Light-Induced Content Release
Liposomes may be stably adsorbed or ruptured on graphene-based materials, depending on the oxidation state of graphene. IR-induced liposome leakage is achieved, since graphene oxide does not induce liposome leakage spontaneously.
Mechanisms of DNA Sensing on Graphene Oxide
(American Chemical Society, 2013-08-20)
Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces a sensor that gives fluorescence enhancement in the presence of its complementary DNA (cDNA). While many important analytical applications have ...
Attaching DNA to Nanoceria: Regulating Oxidase Activity and Fluorescence Quenching
(American Chemical Society, 2013-08-14)
Cerium oxide nanoparticles (nanoceria) have recently emerged as a nanozyme with oxidase activity. In this work, we present a few important interfacial properties of nanoceria. First, the surface charge of nanoceria can be ...
DNA/Metal Oxide Nanoconjugates: Fundamental Understandings and Analytical Applications
(University of Waterloo, 2016-07-29)
DNA-functionalized nanomaterials have shown versatile applications in biosensor development, biomedical diagnostics, therapy, and catalysis. DNA is attractive for this purpose for its programmable structure, molecular ...