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DNA/Metal Oxide Nanoconjugates: Fundamental Understandings and Analytical Applications
(University of Waterloo, 2016-07-29)
DNA-functionalized nanomaterials have shown versatile applications in biosensor development, biomedical diagnostics, therapy, and catalysis. DNA is attractive for this purpose for its programmable structure, molecular ...
Parts-per-Million of Polyethylene Glycol as a Non-Interfering Blocking Agent for Homogeneous Biosensor Development
(American Chemical Society, 2013-11-05)
Many homogeneous assays are complicated by the adsorption of probe molecules by the surface of reaction vessels, which are often made of polypropylene or polystyrene-based plastics. To solve this problem, many protein and ...
Polarity Control for Nonthiolated DNA Adsorption onto Gold Nanoparticles
(American Chemical Society, 2013-05-21)
Gold nanoparticles (AuNPs) functionalized with thiolated DNA have enabled many studies in nanoscience. The strong thiol/gold affinity and the nanoscale curvature of AuNPs allow the attached DNA to adapt an upright conformation ...
Orthogonal Adsorption Onto Nano-Graphene Oxide Using Different Intermolecular Forces for Multiplexed Delivery
(Wiley, 2013-05-31)
Nano-graphene oxide can adsorb both doxorubicin and zwitterionic dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes in an orthogonal and non-competing manner with high capacities based on different surface and intermolecular ...
Attaching DNA to Nanoceria: Regulating Oxidase Activity and Fluorescence Quenching
(American Chemical Society, 2013-08-14)
Cerium oxide nanoparticles (nanoceria) have recently emerged as a nanozyme with oxidase activity. In this work, we present a few important interfacial properties of nanoceria. First, the surface charge of nanoceria can be ...
Mechanisms of DNA Sensing on Graphene Oxide
(American Chemical Society, 2013-08-20)
Adsorption of a fluorophore-labeled DNA probe by graphene oxide (GO) produces a sensor that gives fluorescence enhancement in the presence of its complementary DNA (cDNA). While many important analytical applications have ...
Dissecting Colloidal Stabilization Factors in Crowded Polymer Solutions by Forming Self-Assembled Monolayers on Gold Nanoparticles
(American Chemical Society, 2013-05-21)
An ideal colloidal system should be highly stable in a diverse range of buffer conditions while still retaining its surface accessibility. We recently reported that dispersing citrate-capped gold nanoparticles (AuNPs) in ...
Oxidation Level-Dependent Zwitterionic Liposome Adsorption and Rupture by Graphene-based Materials and Light-Induced Content Release
(Wiley, 2013-04-08)
Liposomes may be stably adsorbed or ruptured on graphene-based materials, depending on the oxidation state of graphene. IR-induced liposome leakage is achieved, since graphene oxide does not induce liposome leakage spontaneously.
Correlation of photobleaching, oxidation and metal induced fluorescence quenching of DNA-templated silver nanoclusters
(Royal Society of Chemistry, 2013-04-07)
Few-atom noble metal nanoclusters have attracted a lot of interest due to their potential applications in biosensor development, imaging and catalysis. DNA-templated silver nanoclusters (AgNCs) are of particular interest ...
Rationally Designed Nucleobase and Nucleotide Coordinated Nanoparticles for Selective DNA Adsorption and Detection
(American Chemical Society, 2013-12-17)
Nanomaterials for DNA adsorption are useful for sequence-specific DNA detection. Current materials for DNA adsorption employ electrostatic attraction, hydrophobic interaction, or π–π stacking, none of which can achieve ...