Browsing Science (Faculty of) by Supervisor "Rose, David"
Now showing items 1-5 of 5
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Deciphering the Indoleacetic Acid Biosynthesis Pathways in the Rhizobacterium Pseudomonas sp. UW4
(University of Waterloo, 2017-09-25)Healthy plants host, within and on the surfaces of their tissues, diverse endophytic and epiphytic bacteria. Often, this interaction is mutualistic, leading to adaptive benefits for both partners. We refer to these ... -
Engineered expression system in K. phaffii for expression of human alpha-glucosidases, their characterization and inhibition
(University of Waterloo, 2020-01-17)This thesis describes a progression of experiments that lead from the design of a new cloning-expression vector for K. phaffii, to the successful expression of numerous human alpha-glucosidases, their characterization and ... -
Starch Glycan Utilization by the Gut Microbiota: Structural and Biochemical Insights Into Starch Digestion and the Role of the Colon Microbiota
(University of Waterloo, 2016-05-12)The human digestive system is resident to a highly populated ecosystem of bacterial species known as the colon microbiota, which contributes significantly to our assimilation of dietary and mucosal carbohydrates. Bacteroides ... -
Structural and Enzymatic Comparison of Faecalibacterium prausnitzii GH31 α-Glycosidases
(University of Waterloo, 2022-05-02)The gut microbiome is home to thousands of species of bacteria, that are essential for human digestion, immunity and physiology. Faecalibacterium prausnitzii makes up about 5% of a healthy human gut microbiome and a lower ... -
A structural investigation of novel fungal polyglycine hydrolases
(University of Waterloo, 2023-03-22)Polyglycine hydrolases (PGH) are a family of fungal proteases that are known to cleave the polyglycine linker of Zea mays chitinase, ChitA, thwarting one mechanism of plant defense against fungal infection. Previously, ...