Browsing Science (Faculty of) by Supervisor "Martin, Dale"
Now showing items 1-2 of 2
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Optimizing protein S-acylation detection in autophagy
(University of Waterloo, 2021-06-04)S-acylation, sometimes referred to as S-palmitoylation or simply palmitoylation, is a posttranslational protein modification involving the covalent addition of a fatty acid to cysteine residues. Since the first characterization ... -
Targeting p62 Palmitoylation as a Potential Therapeutic Strategy towards Huntington Disease
(University of Waterloo, 2023-10-18)Huntington’s Disease (HD) is a neurodegenerative disorder caused by a mutation in the huntingtin gene leading to the accumulation of mutant huntingtin (mHTT) protein and disruption of many cellular pathways causing neuronal ...