Browsing Science (Faculty of) by Subject "superoxide dismutase"
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Aggregation of Amyotrophic Lateral Sclerosis-Associated Cu/Zn Superoxide Dismutase
(University of Waterloo, 2010-05-21)Amyotrophic lateral sclerosis (ALS) is a devastating, progressive, and fatal neurodegenerative disease. Despite the fact that ALS is the most common motor neuron disease in adulthood, there is no effective treatment for ... -
Folding and Stability Studies on Amyotrophic Lateral Sclerosis-Associated apo Cu, Zn Superoxide dismutases
(University of Waterloo, 2009-10-05)Amyotrophic lateral sclerosis (ALS) is a debilitating, incurable, neurodegenerative disease characterized by degradation of motor neurons leading to paralysis and ultimately death in ~3-5 years. Approximately 10% of ALS ... -
A Refined Method for Quantitation of Divalent Metal Ions in Metalloproteins and Local Stability and Conformational Heterogeneity of Amyotrophic Lateral Sclerosis-Associated Cu, Zn Superoxide Dismutase
(University of Waterloo, 2014-05-13)Amyotrophic lateral sclerosis (ALS) is a devastating and progressive disease that results in selective death of motor neurons in the cortex, brain stem and spinal cord. ALS is the most common adult onset motor neuron disease ...