Browsing Science (Faculty of) by Subject "physiology"
Now showing items 1-5 of 5
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Aging affects circadian clock and metabolism and modulates timing of medication
(Elsevier, 2021-04)Aging is associated with impairments in the circadian rhythms, and with energy deregulation that affects multiple metabolic pathways. The goal of this study is to unravel the complex interactions among aging, metabolism, ... -
Aspects of Corneal Fluorescein Staining
(University of Waterloo, 2019-04-25)PURPOSE Evaluating the cornea for epithelial fluorescein staining is a key element of the ocular examination of contact lens wearers and people with dry eye disease. It has long been viewed as a method of visualizing a ... -
Impact of sex and pathophysiology on optimal drug choice in hypertensive rats: Quantitative insights for precision medicine
(Elsevier, 2021-04)Less than half of all hypertensive patients receiving treatment are successful in normalizing their blood pressure. Despite the complexity and heterogeneity of hypertension, the current antihypertensive guidelines are not ... -
The physiological ecology of preparing for and recovering from hibernation in temperate insectivorous bats
(University of Waterloo, 2023-01-12)Temperate insectivorous bats that hibernate must both prepare for and recover from hibernation during times of the year with low resource abundance and low ambient temperatures, resulting in energetic bottlenecks in both ... -
Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Children
(University of Waterloo, 2021-06-25)The following thesis chapters chronicle evolving efforts throughout 2016 – 2021 to support research toward improving the pediatric clinical pharmacology of monoclonal antibodies (mAbs). Translating the benefits of successful ...