Browsing Science (Faculty of) by Subject "nanoparticles"
Now showing items 1-8 of 8
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Antifungal ocular drug delivery via contact lenses using a novel in vitro eye model
(University of Waterloo, 2016-04-21)Purpose: The purpose of this thesis was to evaluate the potential of contact lenses (CLs) as an antifungal drug delivery device, and to develop an in vitro eye model to test thereof. Methods: The first three chapters ... -
Development of Modular Polymeric NPs for Drug Delivery Using Amine-Reactive Chemistry
(University of Waterloo, 2024-01-26)Cancer remains one of the leading causes of death worldwide and very often requires chemotherapy treatment. Despite advances in chemotherapy treatments, some cancers remain difficult to treat due to tumour type, location, ... -
Development of Peptide-Modified Gemini Nanoplexes for Gene Delivery to the Retina
(University of Waterloo, 2020-04-22)Glaucoma is a retinal neurodegenerative disease where the retinal ganglion cells (RGCs) suffer from damage and die over time due to multiple factors, including a persistently elevated intraocular pressure (IOP). Glaucoma ... -
Dynamic mechanical behaviour of nanoparticle loaded biodegradable PVA films for vaginal drug delivery
(Sage Publishing, 2018-03-01)In this study, we investigated the viscoelastic and mechanical behaviour of polyvinyl alcohol films formulated along with carrageenan, plasticizing agents (polyethylene glycol and glycerol), and when loaded with nanoparticles ... -
The effects of multi-walled carbon nanotube exposure on soil organisms
(University of Waterloo, 2013-01-25)With the rapid proliferation of carbon nanotube technologies and consumer products comes a need to research the toxicological and ecotoxicological effects of these materials. This research attempted to develop a baseline ... -
Electroorganic CO₂ Fixation Via Paired Electrolysis and Nanoscale Electrocatalysis
(University of Waterloo, 2023-08-17)Sustainable energy driven electroorganic synthesis provides a green and inexpensive alternative to traditional synthetic approaches. For instance, the electroreduction of many classes of organic molecules enables the ... -
Manipulation of Conducting Oxides and Their Rational Design for Use in Photonics
(University of Waterloo, 2022-06-02)Transparent conducting oxides (TCOs) have been largely studied for their applications in light emitting diodes (LEDs), photodetectors, solar cells, and other photonic uses. TCOs are useful as they can be doped or alloyed ... -
Optical Biosensing Using Localized Surface Plasmon Resonance of Gold Nanoparticles
(University of Waterloo, 2011-05-25)This thesis describes some experiments developed to probe the fundamental aspects of the interfacial behaviour of proteins. The contents of this thesis can be broadly divided into two parts. In the first part, we ...