Browsing Science (Faculty of) by Subject "gemini surfactants"
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Characterization of gemini nanoparticle assembly by fluorescence correlation spectroscopy
(University of Waterloo, 2014-01-23)Research in the field of non-viral gene delivery has demonstrated that a deeper understanding of the fundamental processes of nanoparticle assembly is required in order to improve their efficacy. While gemini nanoparticles ... -
Development of Peptide-Modified Gemini Nanoplexes for Gene Delivery to the Retina
(University of Waterloo, 2020-04-22)Glaucoma is a retinal neurodegenerative disease where the retinal ganglion cells (RGCs) suffer from damage and die over time due to multiple factors, including a persistently elevated intraocular pressure (IOP). Glaucoma ... -
Pharmaceutical Applications of Gemini Surfactants
(University of Waterloo, 2011-01-10)Gemini surfactants are an intriguing class of surface active agents that are comprised of two surfactant monomers chemically linked at or near the headgroups by a rigid or flexible spacer. In comparison to their corresponding ... -
Synthesis and Characterization of Two Pyrene Labeled Gemini Surfactants and their Interactions with Oppositely Charged Molecules
(University of Waterloo, 2022-06-09)Cationic gemini surfactants (GS) have attracted the attention of the scientific community as potential carriers of genetic cargo for gene transfection applications. These GS/polynucleotides complexes have been extensively ...