Browsing Science (Faculty of) by Subject "bacteriophage"
Now showing items 1-4 of 4
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Bacteriophage interactions with mammalian tissue: Therapeutic applications
(Elsevier, 2019-05)The human body is a large reservoir for bacterial viruses known as bacteriophages (phages), which participate in dynamic interactions with their bacterial and human hosts that ultimately affect human health. The current ... -
Bioorthogonal Modification of the Major Sheath Protein of Bacteriophage M13: Extending the Versatility of Bionanomaterial Scaffolds
(American Chemical Society, 2016-09-04)With a mass of ~1.6 x 107 Daltons and com- posed of approximately 2700 proteins, bacteriophage M13 has been employed as a molecular scaffold in bionanomaterials fabrication. In order to extend the versatility of M13 in ... -
Characterization of Bacteriophage λ Displaying Epidermal Growth Factor in the Uptake, Infiltration and Formation of HT29 Spheroids
(University of Waterloo, 2019-07-31)Solid tumours are characterized by a complex structure comprised of extracellular matrix, neoplastic cells and stromal cells, each presenting a barrier to conventional anticancer chemotherapy as well as carrier-mediated ... -
Two Dimensional Genetic Approach to the Development of a Controllable Lytic Phage Display System
(University of Waterloo, 2013-02-22)Bacteriophage Lambda (λ) has played a historical role as an essential model contributing to our current understanding of molecular genetics. Lambda’s major capsid protein “gpD” occurs on each capsid at 405 to 420 copies ...