Browsing Science (Faculty of) by Subject "Proteins"
Now showing items 1-3 of 3
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Characterization of the Distribution of Pyrene Molecules in Confined Geometries with the Model Free Analysis
(American Chemical Society, 2017-12-21)Evidence is provided showing that global Model Free Analysis (MFA) of monomer and excimer fluorescence decays of pyrene dissolved in aqueous solutions of sodium dodecyl sulfate (SDS) provides the same structural and dynamic ... -
Opposing effects of cationic antimicrobial peptides and divalent cations on bacterial lipopolysaccharides
(American Physical Society, 2017-10-09)The permeability of the bacterial outer membrane, enclosing Gram-negative bacteria, depends on the interactions of the outer, lipopolysaccharide (LPS) layer, with surrounding ions and molecules. We present a coarse-grained ... -
Tracing the molecular and evolutionary determinants of novel functions in protein families
(University of Waterloo, 2010-03-29)This thesis explores the limits of homology-based inference of protein function and evolution, where overall similarity between sequences can be a poor indicator of functional similarity or evolutionary relationships. Each ...