Browsing Science (Faculty of) by Subject "Nanoparticles"
Now showing items 1-16 of 16
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Assembly of DNA-Functionalized Nanoparticles in Alcoholic Solvents Reveals Opposite Thermodynamic and Kinetic Trends for DNA Hybridization
(American Chemical Society, 2010-05-12)DNA has been a key molecule in biotechnology and nanotechnology. To date, the majority of the experiments involving DNA have been performed in aqueous solutions, which may be related to the perception that DNA hybridization ... -
Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection
(Royal Society of Chemistry, 2016-03-21)Preserving enzyme activity and promoting synergistic activity via co-localization of multiple enzymes are key topics in bionanotechnology, materials science, and analytical chemistry. This study reports a facile method for ... -
Comparison of Graphene Oxide and Reduced Graphene Oxide for DNA Adsorption and Sensing
(American Chemical Society, 2016-10-18)Fluorescently labeled DNA adsorbed on graphene oxide (GO) is a well-established sensing platform for detecting a diverse range of analytes. GO is a loosely defined material and its oxygen content may vary depending on the ... -
Comparison of MoS2, WS2, and Graphene Oxide for DNA Adsorption and Sensing
(American Chemical Society, 2017-01-17)Interfacing DNA with two-dimensional (2D) materials has been intensely researched for various analytical and biomedical applications. Most of these studies have been performed on graphene oxide (GO) and two metal ... -
Distinction of Individual Lanthanide Ions with a DNAzyme Beacon Array
(American Chemical Society, 2016-06-24)Developing chemical probes to distinguish each lanthanide ion is a long-standing challenge. Aside from its analytical applications, solving this problem will also enhance our knowledge in metal ligand design. Using in vitro ... -
DNA-Functionalized Monolithic Hydrogels and Gold Nanoparticles for Colorimetric DNA Detection
(American Chemical Society, 2010-12-22)Highly sensitive and selective DNA detection plays a central role in many fields of research, and various assay platforms have been developed. Compared to homogeneous DNA detection, surface-immobilized probes allow washing ... -
Förster Resonance Energy Transfer Mediated White-Light-Emitting Rhodamine Fluorophore Derivatives-Gamma Phase Gallium Oxide Nanostructures
(University of Waterloo, 2012-09-26)The global lighting source energy consumption accounts for about 22% of the total electricity generated. New high-efficiency solid-state light sources are needed to reduce the ever increasing demand for energy. Single-phased ... -
Hydrophobic Engineering of a Bacterial Nanodimensional Capsule Protein
(University of Waterloo, 2017-07-07)Recently, numerous protein-based nanomedicine platforms have been intensively explored. These systems are usually composed of self-assembling proteins that form controllable systems with different shapes and types. A ... -
In Vitro Selection in Serum: RNA-Cleaving DNAzymes for Measuring Ca2+ and Mg2+
(American Chemical Society, 2016-05-27)RNA-cleaving DNAzymes have been attempted as in vivo analytical probes and gene silencing reagents over the past two decades. Despite progress already achieved, concerns still exist regarding the activity of DNAzymes in ... -
Iron oxide nanozyme catalyzed synthesis of fluorescent polydopamine for light-up Zn2+ detection
(Royal Society of Chemistry, 2016-07-29)Fluorescent polydopamine (FPD) is an interesting material with excellent biocompatibility. However, its preparation is currently a lengthy and potentially dangerous process. We herein employ magnetic iron oxide (Fe3O4) ... -
Multicopper Laccase Mimicking Nanozymes with Nucleotides as Ligands
(American Chemical Society, 2017-01-18)Using nanomaterials to achieve functional enzyme mimics (nanozymes) is attractive for both applied and fundamental research. Laccases are multicopper oxidases highly important for biotechnology and environmental remediation. ... -
Opposing effects of cationic antimicrobial peptides and divalent cations on bacterial lipopolysaccharides
(American Physical Society, 2017-10-09)The permeability of the bacterial outer membrane, enclosing Gram-negative bacteria, depends on the interactions of the outer, lipopolysaccharide (LPS) layer, with surrounding ions and molecules. We present a coarse-grained ... -
Polymer-stabilized Transition Metal Nanocatalysts: Synthesis, Characterization, and Applications
(University of Waterloo, 2015-01-22)Novel polymeric architectures and analytical methods were designed for the synthesis, characterization, and applications of metallic nanocatalysts. Four main research areas were investigated, namely: i) palladium nanocatalysts, ... -
Programmable Assembly of DNA-Functionalized Liposomes by DNA
(American Chemical Society, 2011-02-22)Bionanotechnology involves the use of biomolecules to control both the structure and property of nanomaterials. One of the most studied examples is DNA-directed assembly of inorganic nanoparticles such as gold nanoparticles ... -
A Silver DNAzyme
(American Chemical Society, 2016-04-05)Silver is a very common heavy metal, and its detection is of significant analytical importance. DNAzymes are DNA-based catalysts; they typically recruit divalent and trivalent metal ions for catalysis. Herein, we report a ... -
Theory and simulation of interactive membrane-macromolecule structures in biological systems
(University of Waterloo, 2014-08-11)This thesis focuses on one of the branches of soft matter: biological systems. More specifically, we study the morphological transformation of lipid bilayer membranes induced by interacting with macromolecules. Recent ...