Browsing Science (Faculty of) by Subject "Inhibition"
Now showing items 1-2 of 2
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Cyclobutanone Analogues of β-Lactam Antibiotics as Inhibitors of Serine- and Metallo-β-Lactamases
(University of Waterloo, 2011-05-31)Bacterial resistance to antibiotics is an emerging epidemic throughout the world and there is a desperate need for new antibiotics and new strategies to maintain the effectiveness of current agents. β-Lactams, such as the ... -
Membrane binding and oligomer formation by the calcium-dependent lipopeptide antibiotic A54145: a quantitative study with pyrene excimer fluorescence
(Elsevier, 2016-09-20)A54145 is a lipopeptide antibiotic related to daptomycin that permeabilizes bacterial cell membranes. Its action requires both calcium and phosphatidylglycerol in the target membrane, and it is accompanied by the formation ...