Browsing Science (Faculty of) by Subject "Cyclobutanone"
Now showing items 1-2 of 2
-
Cyclobutanone Analogues of β-Lactam Antibiotics as Inhibitors of Serine- and Metallo-β-Lactamases
(University of Waterloo, 2011-05-31)Bacterial resistance to antibiotics is an emerging epidemic throughout the world and there is a desperate need for new antibiotics and new strategies to maintain the effectiveness of current agents. β-Lactams, such as the ... -
Synthesis and Chemistry of Carbocyclic Mimics of β-Lactams as β-Lactamase Inhibitors
(University of Waterloo, 2014-10-23)Antibiotics are very important chemical substances, which have saved millions of lives. However, bacterial resistance towards antibiotics, especially the β-lactams, is becoming increasingly serious. Currently, the β-lactam ...