Browsing Science (Faculty of) by Title
Now showing items 988-1007 of 2879
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Exploration of reconstructed PET hydrolase ancestors by biophysical and computational methods
(University of Waterloo, 2023-01-26)Ancestral sequence reconstruction (ASR), originally developed for the study of molecular evolution, has gained attention as a promising method for protein engineering in the recent decade. The ancestors revived by this ... -
An Exploration of Secure Circular Multi-Party Quantum Computation
(University of Waterloo, 2022-09-26)Multi party quantum computation (MPQC) is any quantum cryptographic protocol where multiple untrusted users collaborate to perform calculations on their combined data without revealing their private information. MPQC is ... -
An Exploration of the Scope of GPCR to RTK Transactivation in HT22 and SH-SY5Y cells
(University of Waterloo, 2022-09-02)Receptor tyrosine kinase (RTK) transactivation is a mechanism by which G proteincoupled receptor (GPCR) activity induces the activation of an RTK. As separate families of receptors, they were long thought to act ... -
Exploration of the suitability of coated blade spray for rapid analysis of pesticides in agricultural commodities and byproducts
(University of Waterloo, 2020-09-03)The multiresidue analysis of pesticides in domestic and imported agricultural products is completed on hundreds of thousands of samples yearly by regulatory agencies in the United States, Canada, and Europe. Currently, ... -
Explorations in black hole chemistry and higher curvature gravity
(University of Waterloo, 2018-08-08)This thesis has two goals. The primary goal is to communicate two results within the framework of black hole chemistry, while the secondary goal is concerned with higher curvature theories of gravity. Super-entropic ... -
Explorations in machine learning for interacting many-body systems.
(University of Waterloo, 2020-09-03)Most interacting many-body systems in physics are not analytically solvable. Instead, numerical methods are needed for the study of these complex and high-dimensional problems. At present, there are many interesting problems ... -
Explorations in the Conformal Bootstrap
(University of Waterloo, 2017-07-19)We investigate properties of various conformally invariant quantum systems, especially from the point of view of the conformal bootstrap. First, we study twist line defects in three-dimensional conformal field theories. ... -
Explorations of Black Hole Thermodynamics in de Sitter Spacetime
(University of Waterloo, 2019-01-23)In this thesis I map out two approaches that are foundational to studying black hole thermodynamics in de Sitter spacetime. The first is to understand the "thermodynamic volume" of cosmological horizons in isolation. ... -
Exploring functional annotation through genomic and metagenomic data mining
(University of Waterloo, 2020-09-09)Functional profiling of genomes and metagenomes, as well as data mining for novel proteins, all rely on computational methods for functional annotation of protein sequences. Standard methods assign protein function based ... -
Exploring Ligand Structure and Thermodynamics of the Malachite Green RNA Aptamer
(University of Waterloo, 2012-01-20)RNA aptamers are in vitro sequences of RNA that have a high affinity for their target ligand. They have applications in therapeutics, biosensors and molecular machines. While the practical applications of aptamers are ... -
Exploring Methods for the Characterization of Viral RNA-protein Complexes
(University of Waterloo, 2009-09-24)Flock House virus (FHV) is a (+) ssRNA virus that belongs to the Nodaviridae family. The viral genome is composed of two viral RNA’s: RNA 1 and RNA 2. Deletion and mutation studies in the N- and C-terminus of protein alpha ... -
Exploring microbial diversity across a Southern Ontario landfill
(University of Waterloo, 2019-09-11)Sanitary landfills are highly engineered environments that receive a heterogeneous mixture of organic waste, metals, and plastics. Global waste production continues to grow every year and waste management is an increasing ... -
Exploring new routes to decoherence-free quantum computing; and quantum thermodynamics for fermions
(University of Waterloo, 2020-01-23)This thesis has two parts; the first part is a contribution to the research field of quantum measurement in quantum optics while the second part focuses on quantum thermodynamics for fermionic systems. The aim of the ... -
Exploring the Design of Multiferroic Materials by Nanocrystal Building Block Approach
(University of Waterloo, 2015-12-22)Multiferroic materials have been extensively studied as they exhibit both magnetic and electric properties simultaneously, and could be potential candidate materials for the new generation of magnetoelectric (ME) devices. ... -
Exploring the effect of Spd on early vascular and reproductive development in methylthioadenosine nucleosidase deficient plant embryos
(University of Waterloo, 2019-01-24)Polyamines (PA) are associated with many critical developmental processes, but their mode of action is not known. Biosynthesis of polyamines, ethylene and nicotianamine produce 5’-methylthioadenosine (MTA) as a by-product. ... -
Exploring the energetic and behavioural changes associated with the immune response in zebrafish (Danio rerio)
(University of Waterloo, 2019-09-23)With the world’s population continuously increasing, humanity constantly needs to figure out ways to increase food production to meet growing demands. One way to increase food production that has had exponential growth in ... -
Exploring the foundation of quantum information in quantum optics
(University of Waterloo, 2016-09-21)Quantum information is promising in solving certain computational problems and information security. The power of its speed up and privacy is based on one of the most tested physical theory: quantum mechanics. Many of ... -
Exploring the role of electrolytes in high energy alkali metal batteries
(University of Waterloo, 2016-05-24)With the increasing importance of electrified transport, the need for high energy density storage is also increasing. Possible candidates include lithium air, sodium air and lithium sulphur batteries. One of the major ... -
Exploring the role of teams and technology in patients' medication decision making
(Elsevier, 2019-03)We know little about how electronic health records (EHRs) should be designed to help patients, pharmacists, and physicians participate in interprofessional shared decision making. We used a qualitative approach to understand ... -
Exploring the Structures and Properties of Cationic Aromatic Clusters
(University of Waterloo, 2020-12-02)In this thesis, the structures and properties of protonated aromatic clusters have been investigated. The aromaticity of the phenyl ring can be influenced by the substituents. Electron withdrawing groups (EWGs) can reduce ...