Browsing Science (Faculty of) by Title
Now showing items 705-724 of 3014
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Development of New Domino Reactions of Alkylidene Meldrum’s Acids Involving Friedel-Crafts Chemistry and Catalytic Conjugate Allylation of Alkylidene Meldrum’s Acids
(University of Waterloo, 2009-10-02)Alkylidene Meldrum’s acids are very reactive acceptors in conjugate additions, and are known to be significantly more electrophilic than other α,β-unsaturated carbonyl electrophiles. They also offer advantages in terms of ... -
Development of Novel Molecules as Modulators of Amyloid-β Aggregation
(University of Waterloo, 2021-09-08)Our brain is remarkably special and unique. It has billions of neurons that govern actions and reactions, and enables us to have thoughts, memories, and personality traits – outmost precious assets – that define who we are ... -
Development of novel spme coatings and high-throughput automation of sample preparation for pharmaceutical and clinical samples
(University of Waterloo, 2009-12-23)Increasing the efficiency of the methods used through the development and trial of novel pharmaceutical compounds is an important step to reduce the time required to develop new medical treatments. Before a drug can be ... -
Development of Novel Techniques for Measuring Bulbar Conjunctival Red Blood Cell Velocity, Oximetry and Redness
(University of Waterloo, 2009-04-29)Introduction The ocular surface provides a unique opportunity to study hemodynamics since the vessels can be visualized directly, without treatment and non-invasively. The availability of instruments to measure various ... -
Development of Peptide-Modified Gemini Nanoplexes for Gene Delivery to the Retina
(University of Waterloo, 2020-04-22)Glaucoma is a retinal neurodegenerative disease where the retinal ganglion cells (RGCs) suffer from damage and die over time due to multiple factors, including a persistently elevated intraocular pressure (IOP). Glaucoma ... -
Development of protein level cytokine assays and assessment of the impact of implanted Acoustic Telemetry Tags on the Rainbow Trout (Oncorhynchus mykiss) immune system
(University of Waterloo, 2023-04-06)Telemetry tags are a widely used technology for tracking animals that are difficult to observe in their natural environment. This technology has been increasingly used to monitor and study populations of high value salmonid ... -
Development of RTgutGC as a Tool for Fish Feed Development
(University of Waterloo, 2017-08-15)A rainbow trout intestinal epithelial cell line, RTgutGC, has been used in this thesis to investigate the effects of various stresses in aquaculture on the gastrointestinal (GI) tract and for identifying possible beneficial ... -
Development of Sensitive In Vitro Assays to Assess the Ocular Toxicity Potential of Chemicals and Ophthalmic Products
(University of Waterloo, 2009-04-27)The utilization of in vitro tests with a tiered testing strategy for detection of mild ocular irritants can reduce the use of animals for testing, provide mechanistic data on toxic effects, and reduce the uncertainty ... -
Development of Solid Phase Microextraction Methodologies for the Determination of Anthropogenic Contaminants from Fatty Food Matrices
(University of Waterloo, 2019-09-03)Anthropogenic contaminants have been on the rise worldwide due to global industrialization. The world is now faced with the consequences of the pollution caused by the exposure of man-made chemicals in the environment. ... -
Development of sports-specific classification for Paralympic skiers with visual impairment
(University of Waterloo, 2020-05-28)Introduction: The Paralympic Games are not only a platform for athletes with disabilities to achieve their dreams, but the Games also play a major role in changing societal attitudes towards people with disabilities and ... -
Development of the Aprotic Lithium-Oxygen Battery System
(University of Waterloo, 2015-11-10)With the increasing importance of electrified transport, the need for high energy density storage is also increasing. Possible candidates include Li-O2 batteries, which are the subject of rapidly increasing focus worldwide ... -
Development of the Synthesis of Thiophene and Thiazole Based Conjugated Polymers Through Direct Arylation and The Separation of Carbon Nanotubes Using Degradable Conjugated Polymers
(University of Waterloo, 2023-01-30)Conjugated polymers are an ever-growing field due to their ability to be used for a variety of purposes such as photovoltaics, field-effect transistors, light emitting diodes, and organic sensors. To further this field, ... -
Development of visual acuity and contrast sensitivity in children
(University of Waterloo, 2011-07-11)Purpose: There is little agreement on the age at which visual acuity (VA) and contrast sensitivity (CS) become adult-like. The ultimate purpose of this thesis was to determine whether VA and CS are adult-like at the age ... -
Development, Assessment and Application of Benthic Algal Biomonitoring Protocols for Canadian Waters
(University of Waterloo, 2014-01-24)Stressors such as residential and industrial development and climate warming are escalating in North America, which increases stress to aquatic ecosystems. In the face of this, monitoring biologists must continually improve ... -
Development, Validation, Uptake Rate Modeling and Field Applications of a New Permeation Passive Sampler
(University of Waterloo, 2009-12-15)Passive air sampling techniques are an attractive alternative to active air sampling because of the lower costs, simple deployment and retrieval methods, minimum training requirements, no need for power sources, etc.. ... -
The Developmental History of a Cupriferous Swamp in Southeastern New Brunswick, Canada
(University of Waterloo, 2010-09-30)Cupriferous swamps are characterized by high concentrations of copper in the soil and water. The Aboushagan swamp, situated 8km northwest of Sackville, New Brunswick is a unique metalliferous wetland where copper is ... -
Developments and applications of solid phase microextraction (SPME) coupled to direct analysis in real time (DART) and approaches towards small volume analysis
(University of Waterloo, 2019-08-21)Solid phase microextraction (SPME) has been rapidly developing since its invention in 1990. Due to a flexible design and the ability to implement various extractive coatings, SPME has found use in numerous applications. ... -
Developments in the Centroid Phase Space Formulation of Quantum Statistical Mechanics
(University of Waterloo, 2016-01-25)The centroid formalism provides a phase space representation of quantum statistical mechanics based on the Feynman path integral. Real time quantum correlation functions can be exactly calculated using the centroid formalism, ... -
A Device for Measuring Groundwater Velocity in the Capillary Fringe
(University of Waterloo, 2007-05-22)Groundwater flow in the capillary fringe is rarely measured during hydrogeological studies because of the difficulties associated with investigating this region. Previous research using a point velocity probe (PVP) to ... -
Devices for satellite-assisted quantum networks
(University of Waterloo, 2021-09-24)Quantum networks, quantum nodes interconnected by quantum channels, offer powerful means of secure communications and quantum computations. They are crucial elements in a broad area of quantum technologies including quantum ...