Browsing Science (Faculty of) by Title
Now showing items 1423-1442 of 3014
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Innovative Studies for the Construction of Carbon-Carbon Bonds to Access Synthetically Challenging Scaffolds and Novel Models for Halogen Bonding Studies
(University of Waterloo, 2016-01-28)The formation of carbon-carbon bonds to access sterically challenging all-carbon quaternary centers still remains a synthetic challenge. Conjugate addition reactions have proven to be a very effective strategy for transferring ... -
Insight into Quantitation of Solid-phase Microextraction
(University of Waterloo, 2016-07-21)Solid-phase microextraction (SPME) is a well-known sampling and sample preparation technique used for a wide variety of analytical applications. As there are various complex processes taking place at the time of extraction ... -
Insights into the Effect of the PDMS-Layer on the Kinetics and Thermodynamics of Analyte Sorption onto the Matrix-Compatible Solid Phase Microextraction Coating
(American Chemical Society, 2017-03-07)The currently presented research investigated the performance of matrix compatible PDMS-overcoated fibers (PDMS-DVB/PDMS) as compared to unmodified PDMS/ DVB coatings using aqueous samples and employing a wide range of ... -
Insights into the metabolic regulation of insulin secretion using a metabolomics approach
(University of Waterloo, 2014-06-20)In the post genomic era, metabolomics, as an integrated part of system biology, offers a promising approach to identify biomarkers associated with diseases and hence has been widely used in disease diagnosis, toxicology, ... -
Insights to Using Contact Lenses for Drug Delivery
(Omics International, 2013)There has been considerable interest in the potential application of contact lenses for ocular drug delivery. This short communication provides an overview of the challenges faced by delivering drugs using contact lenses, ... -
Instabilities in Higher-Dimensional Theories of Gravity
(University of Waterloo, 2006)A number of models of nature incorporate dimensions beyond our observed four. In this thesis we examine some examples and consequences of classical instabilities that emerge in the higher-dimensional theories of gravity ... -
Instantaneous and Quantitative Functionalization of Gold Nanoparticles with Thiolated DNA Using a pH-Assisted and Surfactant-Free Route
(American Chemical Society, 2012-05-02)The attachment of thiolated DNA to gold nanoparticles (AuNPs) has enabled many landmark works in nanobiotechnology. This conjugate chemistry is typically performed using a salt-aging protocol where, in the presence of an ... -
Instantaneous Attachment of an Ultrahigh Density of Nonthiolated DNA to Gold Nanoparticles and Its Applications
(American Chemical Society, 2012-12-11)The last 16 years have witnessed the landmark development of polyvalent thiolated DNA-functionalized gold nanoparticles (AuNP's) possessing striking properties within the emerging field of nanobiotechnology. Many novel ... -
Integrability in AdS/CFT: Exacts Results for Correlation Functions
(University of Waterloo, 2012-06-14)We report on the first systematic study of correlation functions in N=4 super Yang-Mills theory using integrability techniques. In particular, we show how to compute three- and four- point functions of single-trace ... -
An Integrated Approach to Paleo-Ice Stream Determination in Mid Continental Prairies, Saskatchewan, Canada
(University of Waterloo, 2009-10-02)Ice stream research has gained momentum in the last decade due to the increased need to understand ice sheet dynamics and instability and, by extension, the role ice streams have on climate change and sea level rise. ... -
Integrated hydrologic model calibration under non-stationary climates
(University of Waterloo, 2024-01-17)With global climate change, quantifying water availability for management under non-stationary conditions is, and will continue to be, a major challenge. When hydrologic models are calibrated to historic climatic conditions, ... -
Integrated Solid Phase, Aqueous Phase and Numerical Investigation of Plume Geochemistry at an Oil Sand Mining Facility
(University of Waterloo, 2006)A plume of process-affected groundwater was identified in a shallow sand aquifer adjacent to a tailings impoundment at Syncrude Canada Ltd. Quantitative and qualitative Naphthenic Acid (NA) analyses were performed on ... -
Integrating Methods for Characterizing the Passive Treatment of Mercury and Selenium in Groundwater and Sediment
(University of Waterloo, 2011-03-16)Standard geochemical analysis methods, such as aqueous geochemistry analysis and mineralogical analysis, frequently are utilized to evaluate the effectiveness of passive treatment systems, though they do not necessarily ... -
Integration of Active and Passive Sampling Techniques for Characterization of Non-point Source Contamination from Septic Systems in Rural Ontario Hamlets
(University of Waterloo, 2019-04-30)Excessive nutrient loading to surface water bodies can lead to the development of eutrophic conditions, including deterioration of water quality and ecological stability. Sources of nutrient loading include wastewater ... -
Integration of Geochemical and Isotopic Analyses of Fracture Minerals and Fluids to Assess the Deep Geological Stability at Chalk River Laboratories, Chalk River, Canada
(University of Waterloo, 2019-09-30)The crystalline bedrock underlying the Chalk River Laboratories (CRL) at Canadian Nuclear Laboratories (CNL) provides a valuable analogue for potential nuclear waste storage sites. As the main pathways for fluid flow in ... -
Integration of non-traditional stable isotopes and synchrotron measurements
(University of Waterloo, 2022-08-31)Selenium is well named after the moon, because statements about this element must often be qualified, making it feel ever changing; for instance, Se is a nutrient, but an excess of 400 µg per day is toxic for humans. High ... -
Integration of paleolimnological and contemporary hydroecological analyses to decipher effects of multiple stressors on water-rich northern landscapes
(University of Waterloo, 2015-09-16)Northern freshwater ecosystems provide important habitat and resources which support abundant wildlife and waterfowl populations and the traditional lifestyle of many First Nation communities. However, concerns have been ... -
Integration of Smart Multidose Blister Packaging for Medication Management
(University of Waterloo, 2022-04-26)Medication non-adherence can lead to non-optimal management of chronic diseases and poor health outcomes. Numerous innovative dispensing products offering real-time medication intake monitoring are being developed and ... -
An integrative study on the controls of mercury (Hg) in the sediments and food webs of thermokarst lakes on the Arctic Coastal Plain of Alaska
(University of Waterloo, 2019-07-26)Arctic freshwater ecosystems are subject to profound climate-driven changes. Air temperatures are rising, leading to changes that include increased primary production and enhanced permafrost degradation. These and other ... -
Intense laser field ionization of atom and molecular ion
(University of Waterloo, 2008-01-24)In order to understand how does the intense laser interact with matter we first of all study the ionization process. In this highly nonlinear region the conventional perturbation theory will fail to predict the experimental ...