Browsing Science (Faculty of) by Title
Now showing items 1048-1067 of 3014
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Exploring functional annotation through genomic and metagenomic data mining
(University of Waterloo, 2020-09-09)Functional profiling of genomes and metagenomes, as well as data mining for novel proteins, all rely on computational methods for functional annotation of protein sequences. Standard methods assign protein function based ... -
Exploring Ligand Structure and Thermodynamics of the Malachite Green RNA Aptamer
(University of Waterloo, 2012-01-20)RNA aptamers are in vitro sequences of RNA that have a high affinity for their target ligand. They have applications in therapeutics, biosensors and molecular machines. While the practical applications of aptamers are ... -
Exploring many-body Physics with Recurrent Neural Networks
(University of Waterloo, 2023-06-22)Originally developed within the natural language processing community, Recurrent neural networks (RNNs) have enabled remarkable progress in speech recognition and machine translation. These architectures belong to the class ... -
Exploring Methods for the Characterization of Viral RNA-protein Complexes
(University of Waterloo, 2009-09-24)Flock House virus (FHV) is a (+) ssRNA virus that belongs to the Nodaviridae family. The viral genome is composed of two viral RNA’s: RNA 1 and RNA 2. Deletion and mutation studies in the N- and C-terminus of protein alpha ... -
Exploring microbial diversity across a Southern Ontario landfill
(University of Waterloo, 2019-09-11)Sanitary landfills are highly engineered environments that receive a heterogeneous mixture of organic waste, metals, and plastics. Global waste production continues to grow every year and waste management is an increasing ... -
Exploring new routes to decoherence-free quantum computing; and quantum thermodynamics for fermions
(University of Waterloo, 2020-01-23)This thesis has two parts; the first part is a contribution to the research field of quantum measurement in quantum optics while the second part focuses on quantum thermodynamics for fermionic systems. The aim of the ... -
Exploring the Design of Multiferroic Materials by Nanocrystal Building Block Approach
(University of Waterloo, 2015-12-22)Multiferroic materials have been extensively studied as they exhibit both magnetic and electric properties simultaneously, and could be potential candidate materials for the new generation of magnetoelectric (ME) devices. ... -
Exploring the effect of Spd on early vascular and reproductive development in methylthioadenosine nucleosidase deficient plant embryos
(University of Waterloo, 2019-01-24)Polyamines (PA) are associated with many critical developmental processes, but their mode of action is not known. Biosynthesis of polyamines, ethylene and nicotianamine produce 5’-methylthioadenosine (MTA) as a by-product. ... -
Exploring the energetic and behavioural changes associated with the immune response in zebrafish (Danio rerio)
(University of Waterloo, 2019-09-23)With the world’s population continuously increasing, humanity constantly needs to figure out ways to increase food production to meet growing demands. One way to increase food production that has had exponential growth in ... -
Exploring the foundation of quantum information in quantum optics
(University of Waterloo, 2016-09-21)Quantum information is promising in solving certain computational problems and information security. The power of its speed up and privacy is based on one of the most tested physical theory: quantum mechanics. Many of ... -
Exploring the role of electrolytes in high energy alkali metal batteries
(University of Waterloo, 2016-05-24)With the increasing importance of electrified transport, the need for high energy density storage is also increasing. Possible candidates include lithium air, sodium air and lithium sulphur batteries. One of the major ... -
Exploring the role of teams and technology in patients' medication decision making
(Elsevier, 2019-03)We know little about how electronic health records (EHRs) should be designed to help patients, pharmacists, and physicians participate in interprofessional shared decision making. We used a qualitative approach to understand ... -
Exploring the Structures and Properties of Cationic Aromatic Clusters
(University of Waterloo, 2020-12-02)In this thesis, the structures and properties of protonated aromatic clusters have been investigated. The aromaticity of the phenyl ring can be influenced by the substituents. Electron withdrawing groups (EWGs) can reduce ... -
Exploring the thermal stability of DNA-linked gold nanoparticles in ionic liquids and molecular solvents
(Royal Society of Chemistry, 2012-11-01)While water is the most commonly used solvent for DNA, many co-solvents have been added for various applications. Ionic liquids (ILs) are molten salts at around room temperature. ILs have been tested as a green solvent for ... -
Exploring the Ventral Hippocampal Formation
(University of Waterloo, 2014-10-23)The hippocampus (HC) is important for both memory and spatial navigation. These functions are thought to be supported by spatial firing patterns of "place cells" which are active in only certain locations within environments. ... -
Expression Inactivating Mechanisms of Major Histocompatibility Class I Alleles in Melanogrammus aeglefinus
(University of Waterloo, 2010-08-30)Melanogrammus aeglefinus, commonly known as haddock, is a commercially important marine fish species closely related to cod. Preliminary investigations into the immune function of this species has revealed several unique ... -
Expression of photosynthetic genes and possible regulatory mechanisms in the single-cell C4 species, Bienertia sinuspersici
(University of Waterloo, 2012-03-15)Bienertia sinuspersici is one of three terrestrial plants identified to perform C4 photosynthesis in a single chlorenchyma cell by compartmentation of organelles and photosynthetic enzymes. This thesis describes a study ... -
Extended Latanoprost Release from Commercial Contact Lenses: In Vitro Studies Using Corneal Models
(Public Library of Science, 2014-10-09)In this study, we compared, for the first time, the release of a 432 kDa prostaglandin analogue drug, Latanoprost, from commercially available contact lenses using in vitro models with corneal epithelial cells. Conventional ... -
Extended thermodynamics of Taub-NUT and Einstein-scalar spacetimes
(University of Waterloo, 2021-08-12)The main objective of this thesis is to summarize recent developments on the thermodynamics of both AdS Einstein-scalar spacetimes and Lorentzian Taub-NUT spacetimes. We summarize and apply well-known techniques in black ... -
Extensive marine anoxia during the terminal Ediacaran Period
(American Association for the Advancement of Science, 2018-06-20)The terminal Ediacaran Period witnessed the decline of the Ediacara biota (which may have included many stemgroup animals). To test whether oceanic anoxia might have played a role in this evolutionary event, we measured U ...