Now showing items 1-4 of 4
A dynamic Mover–Stayer model for recurrent event processes subject to resolution
(Springer US, 2014-07)
In studies of affective disorder, individuals are often observed to experience recurrent symptomatic exacerbations warranting hospitalization. Interest may lie in modeling the occurrence of such exacerbations over time ...
Statistical Issues in Modeling Chronic Disease in Cohort Studies
Observational cohort studies of individuals with chronic disease provide information on rates of disease progression, the effect of fixed and time-varying risk factors, and the extent of heterogeneity in the course of ...
Response-dependent two-phase sampling designs for biomarker studies
Two-phase sampling designs are developed and investigated for use in the context of a rheumatology study where interest lies in the association between a biomarker with an expensive assay and disease progression. We ...
Composite likelihood for joint analysis of multiple multistate processes via copulas
(Oxford Journals, 2014-10)
A copula-based model is described which enables joint analysis of multiple progressive multistate processes. Unlike intensity-based or frailty-based approaches to joint modeling, the copula formulation proposed herein ...