Dynamic transmission models of influenza are often used in decision-making to identify which vaccination strategies might best reduce influenza-associated health and economic burdens. Our goal was to use laboratory confirmed ...

Infectious disease interventions like contact precautions and vaccination have proven effective in disease control and elimination. The priority given to interventions can depend strongly on how virulent the pathogen is, ...

Pair approximation models have been used to study the spread of infectious diseases in spatially distributed host populations, and to explore disease control strategies such as vaccination and case isolation. Here we ...

A within-host model of the spread of tuberculosis is proposed here where the emergence of drug resistance and bacterial dormancy are simultaneously combined. We consider both sensitive and resistant strains of tuberculosis ...

Human and environmental systems are often treated as existing in isolation from one another, whereas in fact they are often two parts of a single, coupled human-environment system. Developing theoretical models of coupled ...

It is widely recognized that coupled socio-ecological dynamics can be qualitatively different from the dynamics of social or ecological systems in isolation from one another. The influence of the type of ecological dynamics ...

The human papillomavirus (HPV) vaccines hold great promise for preventing several cancers caused by HPV infections. Yet little attention has been given to whether HPV could respond evolutionarily to the new selection ...

Mathematical models that couple disease dynamics and vaccinating behaviour often assume that the incentive to vaccinate disappears if disease prevalence is zero. Hence, they predict that vaccine refusal should be the rule, ...

Mathematical models of the interplay between disease dynamics and human behavioural dynamics can improve our understanding of how diseases spread when individuals adapt their behaviour in response to an epidemic. Accounting ...

Early warning signals of sudden regime shifts are a widely studied phenomenon for their ability to quantify a system’s proximity to a tipping point to a new and contrasting dynamical regime. However, this effect has been ...