Now showing items 1-2 of 2
The Design of Intervention Trials Involving Recurrent and Terminal Events
Clinical trials are often designed to assess the effect of therapeutic interventions on the incidence of recurrent events in the presence of a dependent terminal event such as death. Statistical methods based on multistate ...
Sample size and robust marginal methods for cluster-randomized trials with censored event times
In cluster-randomized trials, intervention effects are often formulated by specifying marginal models, fitting them under a working independence assumption, and using robust variance estimates to address the association ...