Browsing Health (Faculty of) by Title
Now showing items 114-133 of 1103
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Cerebral Blood Flow Response to Posture Transition and Walking in Older Adults with Heart Failure
(University of Waterloo, 2019-08-29)Individuals with heart failure (HF) have lower cerebral blood flow (CBF) and oxygenation at rest, and lower cerebral oxygenation at peak exercise, likely due to insufficient cardiac output and poor respiratory function; ... -
Cerebrovascular and cardiovascular responses to lower body negative pressure and posture change in the elderly
(University of Waterloo, 2012-08-27)Lower body negative pressure (LBNP) is frequently used in the research setting as a means to induce orthostatic stress. This tool is applicable to typical movements during daily living only if the associated responses are ... -
Cerebrovascular hemodynamics in older adults: Associations with lifestyle, peripheral vascular health and functional decline
(University of Waterloo, 2013-04-25)In today’s aging population, cerebrovascular health plays a pivotal role in maintaining independence. The identification of early markers of change might help to plan more appropriate preventative and/or therapeutic measures. ... -
Cerebrovascular Hemodynamics, Postural Stability, Gait Dynamics, and Falls in Older Adults
(University of Waterloo, 2018-04-26)Injurious falls in community-living older adults are associated with standing up suggesting that cerebral hypoperfusion following a postural transition might be a contributing factor. A large population study has recently ... -
Changes in Conduit Artery Blood Flow and Diameter Post Blood Flow Restriction
(University of Waterloo, 2011-04-19)Flow mediated dilation (FMD) is a non-invasive test that assesses endothelial health and nitric oxide bioavailability; it is commonly used to examine changes in vascular health due to disease or de-conditioning. Currently, ... -
Changes in Physical Activity, Physical Function and Cognitive Function with Transition to Retirement Living
(University of Waterloo, 2014-08-01)Physical activity is associated with slower physical and cognitive decline with aging. However, there are many barriers to physical activity among community-dwelling older adults. Retirement living may facilitate physical ... -
Changes in whole-blood PUFA and their predictors during recovery from severe acute malnutrition
(Cambridge University Press, 2016-05-28)Children with severe acute malnutrition (SAM) with complications require in-patient management including therapeutic feeding. Little attention has been given to the effects of these feeds on the essential fatty acid status ... -
Changes to Recreational Programming Within the School Environment and Student Physical Activity: A Longitudinal Examination from Year 2 to Year 3 of the COMPASS Study
(University of Waterloo, 2016-05-16)Objective: This study examined the influence of changes to school recreational programming on the prevalence and likelihood of Ontario and Alberta secondary school students meeting the (i) Canadian Society for Exercise ... -
Characterization of a novel truncated isoform of murine AGPAT4 arising from predicted splice variants
(University of Waterloo, 2021-06-02)The acylglycerophosphate acyltransferase (AGPAT)/lysophosphatidic acid acyltransferase (LPAAT) family of enzymes is responsible for the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor of ... -
Characterization of Changes in the Kidney, Liver, and Adipose Tissue of RTSAKO Mice
(University of Waterloo, 2018-11-02)Our laboratory has developed a novel genetic mouse model with kidney-specific lipid accumulation called RTSAKOs. The principle aim of my thesis was to study differences in the expression of genes and proteins related to ... -
Characterization of murine HRASLS-1: transcript variant analysis, metabolic regulation, developmental expression, and a role in inflammation
(University of Waterloo, 2014-08-27)N-acylethanolamides (NAE) are involved in a variety of biological processes ranging from fat oxidation to inflammation mediation. Recently, the HRASLS family, a group of class II tumour suppressor proteins, have been ... -
Characterization of the critical biochemical and physiological role of 1-acylglycerol-3-phosphate-O-acyltransferase 4 (AGPAT4) in white adipose tissue
(University of Waterloo, 2016-08-18)White adipose tissue (WAT) is an endocrine and lipid storage organ that is imperative to mammals for the maintenance of energy homeostasis. WAT depot size and triacylglycerol (TAG) content is determined by the regulation ... -
Characterization of the effect of the menstrual cycle, estradiol and Fads2 transcript variants on fatty acid composition and enzyme expression
(University of Waterloo, 2016-08-29)Estrogen is believed to regulate fatty acid composition based on observations of differences between men and women, and changes associated with altered estrogen levels in women during pregnancy, menopause and hormone ... -
Characterization of the effects of sex, pregnancy, and 17β-estradiol on docosahexaenoic acid biosynthesis
(University of Waterloo, 2013-09-27)Docosahexaenoic acid (DHA) is an omega-3 polyunsaturated fatty acid (n-3 PUFA) required for fetal neurodevelopment. Increased DHA levels are associated with 17β-estradiol levels, as DHA is higher in women relative to men ... -
Characterization of the Human Plasma Macrolipidome using Standard Reference Material 1950 - Metabolites in frozen human plasma
(University of Waterloo, 2022-01-26)Standard Reference Material (SRM) 1950 Metabolites in frozen human plasma is a pooled plasma sample created by the National Institute of Standards and Technology (NIST) to be representative of plasma from the population ... -
Characterizing a Novel Enzyme Involved in Cardiolipin Remodelling
(University of Waterloo, 2023-12-05)Background: Cardiolipin (CL) is a specialized dimeric phospholipid comprising approximately 25% of total phospholipids in the inner mitochondrial membrane in eukaryotes, where it functions in energy metabolism, autophagy ... -
Characterizing poly-substance use and its associations with anxiety and depression among a sample of Canadian high school students
(University of Waterloo, 2022-01-05)In any given year, one in five Canadians experience mental illness. The majority of mental illnesses originate in adolescence or young adulthood. Many complex factors can contribute to this, including substance use. However, ... -
Characterizing Sex Differences in Lipid Metabolism during an Acute, 30-Minute Bout of Moderate- Intensity Continuous (MIC) Exercise
(University of Waterloo, 2021-01-05)INTRODUCTION: Increased intramyocellular lipid (IMCL) size and storage in the subsarcolemmal region of the myocyte are associated with insulin resistance (IR) and the development of type 2 diabetes (T2D). Women have a ... -
Characterizing Sex Differences in Skeletal Muscle Anaerobic Metabolism during an Acute Bout of High Intensity Interval Exercise
(University of Waterloo, 2020-09-03)INTRODUCTION: Exercise is known to improve insulin sensitivity (IS); however, its effectiveness may be absent or blunted in women, particularly following high intensity interval (HII) training. Sex differences in anaerobic ... -
Characterizing site-specific body composition of older adults and their associations with strength, functional capacity, and metabolic health
(University of Waterloo, 2021-06-03)Background: Ageing is associated with skeletal muscle atrophy and increased intramuscular adipose tissue. Emerging evidence indicates that specific muscle groups may be largely responsible for the ageing-related degradation ...