Browsing Health (Faculty of) by Author "Chambers, Paige"
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The Effects of a Calcineurin Inhibitor on Muscle Fibre Type and the Pathology of Centronuclear Myopathy in PlnOE Mice
Chambers, Paige (University of Waterloo, 2017-01-27)The sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) pump is responsible for pumping calcium from the cytosol back into the lumen of the sarcoplasmic reticulum post contraction. SERCA activity can be reduced by an inhibitory ... -
The Role of Sarcolipin in Muscle Adaptation with Aging
Chambers, Paige Jilleia (University of Waterloo, 2024-04-08)The sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pump facilitates the transport of Ca2+ against a concentration gradient from the cytosol to the lumen of the SR, eliciting relaxation and maintaining Ca2+ homeostasis. ...