Browsing Health (Faculty of) by Author "Juracic, Emma Sara"
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Characterizing the Role of Phospholamban in Duchenne Muscular Dystrophy
Juracic, Emma Sara (University of Waterloo, 2018-01-16)Duchenne muscular dystrophy (DMD) and the murine model, mdx, are recessive X-linked myopathies characterized by aberrant Ca2+-handling resulting in muscle atrophy and weakness. Phospholamban (PLN) is a protein inhibitor ... -
Characterizing the Roles of Myoregulin and Dwarf Open Reading Frame in Regulating Calcium Homeostasis in Muscle
Juracic, Emma Sara (University of Waterloo, 2024-01-26)The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) are responsible for inducing muscle relaxation and are integral to the maintenance of intracellular calcium (Ca2+) homeostasis. As such, their activity is modulated ...