Browsing Theses by Supervisor "Moo-Young, Murray"
Now showing items 1-6 of 6
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Application of hydrocarbon and perfluorocarbon oxygen vectors to enhance heterologous production of hyaluronic acid in engineered Bacillus subtilis
(University of Waterloo, 2017-12-19)In microbial cultivations for hyaluronic acid (HA) production, oxygen can be a limiting substrate due to its poor solubility in aqueous medium and the substantial increase in culture viscosity at relatively low HA titers. ... -
Characterization and Improvement of Oxygen Mass Transfer in a Rocking Disposable Bioreactor
(University of Waterloo, 2020-06-04)Rocking disposable bioreactors use a cyclic rocking motion to induce mixing and oxygen transfer from the headspace gas into the liquid and are a novel type of bioreactor currently suitable for smaller-scale cell growth. ... -
A comprehensive CRISPR-Cas9 toolkit for Bacillus subtilis: development for biomanufacturing applications
(University of Waterloo, 2018-04-30)Bacillus subtilis is a model Gram-positive GRAS organism sought after for its robust growth characteristics in inexpensive media, genetic tractability, and ability to secrete products into the extracellular environment. ... -
Development of nanocatalytic-based assay for the detection of an endocrine disrupting compound in aqueous solution
(University of Waterloo, 2016-03-09)Endocrine disrupting compound (EDC) pollutants raise a concern among researchers as these pollutants are implicated in the increasing incidence of testicular, breast and thyroid cancers. Some of these chemicals are widely ... -
Integrated metabolic engineering and bioprocessing strategies for production of succinyl-CoA-derived chemicals in Escherichia coli
(University of Waterloo, 2020-09-15)Due to various social, environmental, and technological issues associated with petro-based chemical processes, bio-based production using microbial cell factories has been recognized as a modern biotechnology for more ... -
Manipulating the Sleeping Beauty Mutase Operon in Engineered Escherichia Coli for Controlled Biosynthesis of 1-Propanol and Other Value-Added Chemicals
(University of Waterloo, 2016-05-02)A great fraction of the world’s energy requirements are presently met through the unrestricted use of fossil-derived fuels. However, due to the anticipated demise of these energy sources and the environmental and socioeconomic ...