Browsing Theses by Supervisor "Lu, Qing-Bin"
Now showing items 1-4 of 4
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Evaluation and Comparison of Two Novel Non-Platinum-Based Antitumor Agents on Pancreatic Cancer and Triple-Negative Breast Cancer
(University of Waterloo, 2022-10-03)Cancer is one of the leading causes threatening human life. People suffering from pancreatic cancer and triple-negative breast cancer (TNBC) have particularly low survival rate among all cancer types. The novel non-platinum ... -
In vitro test of a potential hypoxic radiosensitizer
(University of Waterloo, 2016-09-28)Oxygen has long been known as a potent radiosensitizer that can enhance the cell killing effects in aerobic cells, while pruned vasculatures and lack of oxygen in the microenvironment of tumor can cause resistance to ... -
A Novel Combination Therapy of Cisplatin with a Molecular Promoter for Cancer Treatment
(University of Waterloo, 2017-01-25)Cisplatin is the first and most widely used platinum-based chemotherapy drug and is the cornerstone agent in treating a broad spectrum of cancers, including ovarian cancer, testicular cancer, cervical cancer, bladder cancer, ... -
Physiologically based Pharmacokinetic (PBPK) Modelling of Cisplatin in Rats and Humans
(University of Waterloo, 2019-10-17)The physiologically based pharmacokinetic (PBPK) modelling has been accepted as one of the most effective mechanistic techniques to analyze pharmacokinetics (PK) of drugs in the drug development process. Its effectiveness ...