Browsing Theses by Subject "Drug delivery"
Now showing items 1-6 of 6
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Carbon Nanotubes as Versatile Devices for Detoxification and Cellular Entry
(University of Waterloo, 2012-10-30)The ability to bypass most cellular barriers to gain access to intracellular compartments has great potential in cell biology. The possibilities range from efficient delivery of macromolecules such as plasmids to small ... -
Design, Fabrication and Control of a Magnetic Capsule Robot for the Human Esophagus
(University of Waterloo, 2010-02-19)Biomedical engineering is the application of engineering principles and techniques to the medical field. It combines the design and problem solving skills of engineering with medical and biological sciences to improve ... -
Dynamic Modeling of Drug Transport in Solid Tumors and Optimal Chemotherapy Regimen
(University of Waterloo, 2015-09-30)One of the most common therapies for treatment of cancer patients is chemotherapy. Therapeutic agents (drugs) can kill cancer cells by damaging their DNA and interrupting their extensive proliferation. Successful chemotherapy ... -
Numerical Modeling of Drug Delivery to Solid Tumor Microvasculature
(University of Waterloo, 2013-01-25)Modeling interstitial fluid flow involves processes such as fluid diffusion, convective transport in the extracellular matrix, and extravasation from blood vessels. In all of these processes, computational fluid dynamics ... -
Potential of surface modified exosomes for extended intravitreal drug delivery
(University of Waterloo, 2021-04-30)Diabetic retinopathy is a serious condition affecting retinal cells that can lead to blindness. Intravitreal injection is the only feasible method of drug delivery to the retina. However, intravitreal injections are only ... -
Self/Co-Assembling Peptide-based Nanocarriers for Anticancer Drug Delivery
(University of Waterloo, 2014-04-24)Current diagnostic and therapeutic nanocarriers, including liposomes, micelles, and polymeric- and protein-based nanoparticles, are designed to have key functional properties such as: (i) longevity in the bloodstream, ...