Browsing Theses by Title
Now showing items 7360-7379 of 15557
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In-Silico Methods for De-Risking the Clinical Development of Subcutaneously Administered Therapeutic Macromolecules
(University of Waterloo, 2016-07-27)Prediction of human pharmacokinetics (PK) following subcutaneous (SC) administration to animals is challenged by potential interspecies differences in skin anatomy and physiology. With respect to biologic or macromolecule ... -
In-Situ Chemical Oxidation of Oil Sands Process Affected Groundwater
(University of Waterloo, 2014-12-01)Development of oil sands mining in Athabasca basin, NE Alberta has resulted in generation of more than 1 × 109 m3 of oil sands process-affected water (OSPW) mixed with fine tailings and currently stored in about 182 km2 ... -
In-Situ Continuous Monitoring of Catastrophic Phase Inversion and Viscosity of Pickering Emulsions
(University of Waterloo, 2018-05-22)Emulsions are used in the various field such as petroleum, pharmaceuticals, foods, cosmetics, paints, etc. Emulsions stabilized with solid nanoparticles are called Pickering emulsions. More recently, a growing awareness ... -
In-Situ Ethylene Polymerization with Organoclay-Supported Metallocenes for the Preparation of Polyethylene-Clay Nanocomposites
(University of Waterloo, 2010-05-20)In-situ polymerization is one of the most efficient methods for production of polymer clay nanocomposites. In-situ polymerization of olefins using coordination catalysts is a type of heterogeneous polymerization. In order ... -
In-situ MnO2 Electrodeposition and its Negative Impact to Rechargeable Zinc Manganese Dioxide Batteries
(University of Waterloo, 2018-12-19)Achieving high rechargeability with the economically feasible and environmentally friendly Zn-MnO2 batteries has been the goal of many scientists in the past half century. Recently, the stability of the system saw a ... -
In-situ monitoring and intermittent controller for adaptive trajectory generation during laser directed energy deposition via powder feeding
(University of Waterloo, 2023-03-27)Laser Directed Energy Deposition (LDED) is one of the advanced manufacturing technologies for building near-net-shaped engineering components in a layer-by-layer fashion using high-power lasers as an energy source. LDED ... -
In-Situ Monitoring and Quality Assurance Algorithms for Laser Powder-Bed Fusion
(University of Waterloo, 2022-04-13)This dissertation describes the development of advanced in-situ defect detection algorithms using analytical and machine learning methods, followed by intermittent control systems to minimize the number of defects in parts ... -
In-Situ Polymerizatioon and Characterization of Polyethylene-Clay Nanocomposites
(University of Waterloo, 2008-01-22)Abstract Chapter 1 provides an overview of this study and a literature review. Emphasis is put on the materials used, the different processes available to synthesize polymer-clay nanocomposites, analytical methods to ... -
In-Situ TiC-Fe Deposition on Mild Steel Using a Laser Cladding Process
(University of Waterloo, 2011-08-26)The growing interest in increasing the wear resistance and hardness of surfaces that are in contact with abrasives or corrosive materials has inspired the development of several processes for creating protective coatings. ... -
In-solution and physical state properties of polymer and lipid excipients and their effects on the supersaturation evolution of poorly water-soluble drugs
(University of Waterloo, 2023-04-14)Solubility has become an increasing issue for the pharmaceutical industry, as the advances in combinatorial chemistry and high throughput screening methods have resulted in an increase in the molecular weight and lipophilicity ... -
In-Tip Solid Phase Microextraction for High Throughput Drug Analysis
(University of Waterloo, 2011-09-30)This thesis describes the design of a convenient format of solid phase microextraction (SPME) for bioanalysis in pharmaceutical industry and the validation of the approach to the application. An automated in-tip SPME ... -
In-vehicle Performance and Distraction for Midair and Touch Directional Gestures
(University of Waterloo, 2023-07-18)We compare the performance and level of distraction of expressive directional gesture input in the context of in-vehicle system commands. Center console touchscreen swipes and midair swipe-like movements are tested in ... -
An In-Vitro and Finite Element Investigation on the Efficacy of Unloader Knee Braces on Meniscus Strain and Tibiofemoral Pressure
(University of Waterloo, 2023-09-26)The medial and lateral menisci, situated in the knee joint, are most injured soft tissues in the human body. Meniscus injuries can be isolated or occur concurrently with an anterior cruciate ligament (ACL) injury. Certain ... -
In-vitro selection, characterization and application of a silver-specific DNAzyme
(University of Waterloo, 2019-01-07)Evolution of novel DNA-based catalysts (DNAzymes) through in-vitro selection has expedited the research by manifolds, in both fundamental and analytical aspects of bio-nanotechnology. DNAzymes are attractive for their high ... -
[in]formal Pattern Language - A guide to Handmade Improvitecture© in Cairo
(University of Waterloo, 2015-10-30)The thesis is situated in Cairo, a city with 64% of the population living in informal settlements. Cairo‘s informality transcends, however, the boundaries of these areas and manifests itself daily in spatial and temporal ... -
InAs/AlSb Based Mid-Infrared QCL Growth and XRD Simulation
(University of Waterloo, 2016-08-24)In the past two decades, mid-infrared (MIR) quantum cascade laser (QCL) research has been rapidly developed and has resulted in an enabling platform for the remote sensing and metrology. QCL is designed by spatial confinement ... -
iNaturalist: Understanding Biodiversity Through a Digital Medium
(University of Waterloo, 2018-01-23)Much of the current excitement about citizen science is due to the innovative use of internet-based media platforms. These are designed to enable data production while seeking to be instructive or even entertaining for its ... -
Incentive Design of Conservation Voltage Reduction Planning for Industrial Loads in Ontario
(University of Waterloo, 2013-09-25)In this thesis, a novel framework for planning and investment studies pertaining to the implementation of system-wide conservation voltage reduction (CVR) is presented. In the CVR paradigm, optimal voltage profiles at the ... -
Incentive-Based Expansion Planning and Reliability Enhancement Models for Smart Distribution Systems
(University of Waterloo, 2018-10-01)Due to the rapid progress toward the implementation of smart grid technologies, electric power distribution systems are undergoing profound structural and operational changes. Climate concerns, a reduction in dependency ... -
Incentives in One-Sided Matching Problems With Ordinal Preferences
(University of Waterloo, 2016-07-27)One of the core problems in multiagent systems is how to efficiently allocate a set of indivisible resources to a group of self-interested agents that compete over scarce and limited alternatives. In these settings, mechanism ...