Browsing Theses by Title
Now showing items 11565-11584 of 15526
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Protein Structure Elastic Network Models and the Rank 3 Positive Semidefinite Matrix Manifold
(University of Waterloo, 2019-01-09)This thesis is a contribution to the study of protein dynamics using elastic network models (ENMs). An ENM is an abstraction of a protein structure where inter-atomic interactions are assumed to be modelled by a Hookean ... -
Proteomic analyses of plant-bacterial interactions
(University of Waterloo, 2010-05-27)Proteome-level changes of both the plant growth-promoting bacterium (PGPB) Pseudomonas putida UW4 and its plant host Brassica napus (canola) were profiled using two-dimensional (2-D) difference in-gel electrophoresis (DIGE) ... -
Proteomic Analysis and Long Term Live Cell Imaging of Primary Human Cells in Culture
(University of Waterloo, 2011-08-18)Regenerative medicine is a rapidly developing field, merging engineering and biological life sciences to create biological replacements for damaged tissue and organ function. Development of cellular based therapies has the ... -
Proteomic Analysis of Chinese Hamster Ovary Cells Producing Glycosylated Monoclonal Antibodies
(University of Waterloo, 2013-06-19)Therapeutic monoclonal antibodies (MAb) are produced as secreted complex glycoproteins from mammalian cell systems and represent one of the most important classes of therapeutic medicines for the treatment of a variety of ... -
Proteomics Analysis of Protein-Producing Chinese Hamster Ovary Cells during Apoptosis in Prolonged Cultivation
(University of Waterloo, 2010-05-21)Among the factors important for maintaining productivity of recombinant proteins in mammalian cells, culture lifetime, cell density and cell viability are three simple but essential aspects that can greatly influence the ... -
Proterozoic zircon dates from auriferous zones at the Island Gold deposit: implications for late gold remobilization in the Superior Province
(University of Waterloo, 2024-02-13)The Island Gold deposit is a high-grade Archean orogenic gold deposit within the Michipicoten greenstone belt of the Superior Province. Hosted within the ~2750 Ma felsic to intermediate Wawa metavolcanic assemblage, gold ... -
Protest for New Protocols: What the Debate on the Duty to Consult Says about the State of Indigenous-settler Relationships
(University of Waterloo, 2014-08-21)Indigenous-settler relationships in Canada are grounded in constitutional obligations. When actors dispute the terms of Indigenous-settler relationships, these actors are seeking to change the nature and scope of existing ... -
Protocol development for reliable isolation of tear-film neutrophils and in vitro functionality testing
(University of Waterloo, 2019-09-19)During prolonged eye closure, such as during sleep, leukocytes are recruited to the ocular surface, with polymorphonuclear neutrophils (PMNs) representing the largest population. PMNs are essential inflammatory cells ... -
A protocol for constructing a domain-specific ontology for use in biomedical information extraction using lexical-chaining analysis
(University of Waterloo, 2007-01-19)In order to do more semantics-based information extraction, we require specialized domain models. We develop a hybrid approach for constructing such a domain-specific ontology, which integrates key concepts from the ... -
A Proud Legacy, A New Future: Bringing Ottawa's Growth Management Strategy Into the 21st Century
(University of Waterloo, 2007-09-26)As Canada’s capital, the City of Ottawa has benefited from several comprehensive land use planning exercises since the early 1900s. Early plans carried out by the federal government were led by Prime Ministers who, in ... -
The Prouhet-Tarry-Escott problem
(University of Waterloo, 2013-01-15)Given natural numbers n and k, with n>k, the Prouhet-Tarry-Escott (PTE) problem asks for distinct subsets of Z, say X={x_1,...,x_n} and Y={y_1,...,y_n}, such that x_1^i+...+x_n^i=y_1^i+...+y_n^i\] for i=1,...,k. ... -
Providing Context in WS-BPEL Processes
(University of Waterloo, 2008-09-24)Business processes are increasingly used by organizations to automate their activities. Written in languages like WS-BPEL, they allow an institution to describe precisely its internal operations. As the pace of change ... -
Providing Freshness for Cached Data in Unstructured Peer-to-Peer Systems
(University of Waterloo, 2013-04-17)Replication is a popular technique for increasing data availability and improving perfor- mance in peer-to-peer systems. Maintaining freshness of replicated data is challenging due to the high cost of update management. ... -
Provincial Class Environmental Assessment: The Examination of Whether the Process can be Effectively Applied in a Northern Ontario Context
(University of Waterloo, 2010-04-30)As Canada employs a federated system of government, there are separate environmental assessment (EA) processes. In Ontario, Canada, there is a streamlined, pre-approved, self-assessed process (i.e., the Minister of the ... -
Proving Properties of Fibonacci Representations via Automata Theory
(University of Waterloo, 2024-01-22)In this work, we introduce a novel framework for mechanically testing the completeness and unambiguity of Fibonacci-based representations via automata theory. We call a representation (or a number system) complete and ... -
Provision Quality-of-Service Controlled Content Distribution in Vehicular Ad Hoc Networks
(University of Waterloo, 2012-08-30)By equipping vehicles with the on-board wireless facility, the newly emerged vehicular networking targets to provision the broadband serves to vehicles. As such, a variety of novel and exciting applications can be provided ... -
Provisional Zones
(University of Waterloo, 2018-05-18)Provisional Zones is an installation made up of found or discarded objects to which I apply paint or painterly conventions. I do this to make something new from that which was forgotten or unremarkable. I place unusual ... -
Provocation of the Non-Place [A Place for Alienation]
(University of Waterloo, 2009-08-17)The “non-place” is a term used by author Marc Augé to describe a place that is itself not a destination but rather a place of everyday passing, a place of being in-between in which he critically claims we experience ... -
The Proximon: Representation, Evaluation, and Applications of Metagenomic Functional Interactions
(University of Waterloo, 2017-09-19)The effective use of metagenomic functional interactions represents a key prospect for a variety of applications in the field of functional metagenomics. By definition, metagenomic operons represent such interactions but ... -
PRSONA: Private Reputation Supporting Ongoing Network Avatars
(University of Waterloo, 2021-12-09)Trust and user-generated feedback have become increasingly vital to the normal functioning of the modern internet. However, deployed systems that currently incorporate such feedback do not guarantee users much in the way ...